Our privacy policy has changed. By using this site, you agree to the Privacy Policy and Terms of Use. Dismiss

CTSI funds ovarian cancer research

Aug. 21, 2014

A research scientist from the Medical College of Wisconsin (MCW) has received a three-year Mentored Career Development Award from the Clinical & Translational Science Institute of Southeast Wisconsin (CTSI) to study the effects of mesothelial cells on patient-derived ovarian cancer spheroids (clusters of ovarian cancer cells).

Erin Bishop, M.D., assistant professor of obstetrics and gynecology at MCW and a practicing gynecologic oncologist at Froedtert Hospital, is the recipient of one of four grants awarded this year by the CTSI. The grant provides up to $140,000 per year in salary and benefits, as well as $25,000 to support her research. In addition to the financial support, the grant also provides mentored training opportunities for junior faculty working in clinical and translational research who want to become dedicated, independently funded researchers. Dr. Bishop’s mentor over the next three years is Ramani Ramchandran, Ph.D., vice chair of Research Obstetrics and Gynecology, Patrick J. and Margaret G. McMahon Professor of Obstetrics and Gynecology, professor of pediatrics and developmental biology and human molecular embryology at the MCW, and an investigator at the Children’s Hospital of Wisconsin Research Institute.

Mesothelial cells are cells that line the internal organs and body wall around the abdomen, the lungs, and the heart. The goal of this project is to investigate the effects of mesothelial cells on adhesion and invasion of patient-derived ovarian cancer spheroids (3-dimensional cells) compared to single ovarian cancer cells in vitro, or studied outside normal biological context.

Drs. Bishop and Ramchandran will also focus on the clinical behavior of patient-derived ovarian cancer spheroids compared to single cells and determine if spheroids resist chemotherapy. Doing so will help determine the role of mesothelial cells in triggering ovarian cancer spheroid linkage, invasion, and spreading of cancer cells.

The goal of the CTSI is to create synergy through collaboration, and studies are specifically designed to lead to major future research support. The projects explore findings that have the potential to be translated into clinical practice and community health, and are led by investigators at the CTSI’s eight partnering institutions: the Medical College of Wisconsin, Marquette University, Milwaukee School of Engineering, UW-Milwaukee, Froedtert Hospital, Children’s Hospital of Wisconsin, the Clement Zablocki VA Medical Center, and Blood Center of Wisconsin.

CTSI is one of only 62 medical research institutions funded by the National Institutes of Health (NIH). Working together, the CTSI institutions are committed to improving human health by streamlining science, transforming training environments and improving the conduct, quality and dissemination of clinical and translational research. The CTSI program is led by the National Center for Advancing Translational Sciences (NCATS), part of the NIH.

Support for the Mentored Career Development Award Program is provided through the CTSI.

Community Watch

» Shoulder mount of beloved deer 'Bow Tie' to return to Milwaukee Co. Parks 03:41 PM

» Video Tosa Top 5: Five things you need to know about in Wauwatosa this week 02:35 PM

» Sports Shorts: May 5, 2016 5/4

» Wauwatosa East batters come to life against Brown Deer, Brookfield East 5/4

» Wauwatosa East boys track team finishes fourth at Dan Benson Invite 5/4

» Wauwatosa golfers win Panther Invite 5/4

» Wauwatosa West softball team holds on to nip Port Washington 5/4

» Wauwatosa East girls track team finishes fourth at Dan Benson Invite 5/4

» Adams leads the way for Wauwatosa West girls at Dan Benson Invite 5/4

» Wauwatosa West boys track and field team finishes fifth at Dan Benson Invite 5/4

» Initial Reaction Podcast: Schobert, Watt, Packers and social media foibles of NFL Draft 5/2

» Travis Hudson earns third straight volleyball National Player of the Year Award 5/2

» Wauwatosa East student named 2016 presidential scholar 5/2

» Tosa Tonight announces 2016 concert headliners 5/2

» 360NOW: Wander Wawatosa's village 4/29

» Milwaukee Co. Zoo welcomes new female giraffe calf 4/29

» Video Tosa Top 5: Five things you need to know about in Wauwatosa 4/28

» Wauwatosa seeks volunteers for focus groups on city communication 4/28

» Show about solitary confinement encourages discussion, activism 4/28

» Annual Tosa Night Out celebration will relocate to Milwaukee County Zoo Updated:  4/27

» District leaders question use of Wauwatosa schools as voting locations Updated:  4/27

» Area businesses collaborate to create the 'Cranky Sammie' in East Tosa 4/27

» Wauwatosa Sports Notes: Players sign with colleges, baseball fundraiser, more 4/26

» Wauwatosa West sprinters stand out at Kansas Relays 4/26

» Wauwatosa West' Hannah-Howell, Jefferson shine at Sun Prairie Track Meet 4/26

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where our Wauwatosa reporter explores the closed down and closed off parts of Wauwatosa.

Advertisement

CONNECT