NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
30°
H 32° L 25°
Cloudy | 6MPH

MCW to design national clinical trial for treatment of a lung disease in primary immunodeficiency

Aug. 8, 2014

The Medical College of Wisconsin (MCW) and the Children’s Hospital of Wisconsin Research Institute have received a one-year, $280,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to design a multi-center clinical trial.

John Routes, M.D., professor and chief of asthma, allergy, and immunology at MCW and medical director of asthma, allergy and clinical immunology at Children’s Hospital of Wisconsin, is the primary investigator on the project.

Common variable immune deficiency (CVID) is a fairly rare disorder (1 in 25,000) that impairs the immune system, making people highly susceptible to infections. Ten to 15 percent of patients with CVID develop a complication called granulomatous/lymphocytic interstitial lung disease (GLILD), which is a progressive disease that restricts the ability to breathe, and is a significant cause of death in immune-compromised patients who develop GLILD.

There is no established standard of care for treating GLILD. However, Dr. Routes’ research team recently found an immunosuppressive therapy using two FDA-approved drugs improved the lung function in a select group of patients with GLILD.

With this grant funding, Dr. Routes will design a multicenter, placebo controlled trial for patients with GLILD. Designing a trial includes recruiting a sufficient number of investigators and centers, developing a leadership structure, establishing clinical and scientific cores, creating regulatory documents and manuals of procedures, and developing a database for data collection.

This project is supported by NIH grant R34 AI106570-01A1.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Student in custody for bringing knives to Wauwatosa East High School 3/3

» OSHA says drill rig involved in construction worker's death Updated:  3/3

» Twirly Birds vintage store plans return to Wauwatosa 3/2

» Dry cleaner seeks expansion into old City Market in Wauwatosa 3/2

» 'Momastery' author coming to Wauwatosa 2/27

» Wauwatosa's Folley and Reagan advance to state wrestling semis 2/26

» Wauwatosa East teacher Barb Bruesewitz named ProStart Teacher of the Year 2/26

» Pancake breakfast Sunday will raise money for scholarships 2/25

» Read the winning essays in Tosa's All-City Read contest 2/24

» Victim in fatal Wauwatosa house fire was 3-year-old girl Updated:  2/23

» MMSD commission OKs $6.4 million flood control project 2/23

» Medical examiner identifies 3-year-old who died in Wauwatosa house fire 2/22

» Menomonee flood plan would free part of stream from culvert 2/20

» Five idling cars stolen in one week in Wauwatosa 2/20

» Two men attempted to defraud two Apple stores with fake iPhones 2/20

» National German Exam qualifies some students for study abroad 2/20

» Personal finance students at Wauwatosa West guess value of items in "The Twelve Days of Christmas" 2/19

» Wauwatosa woman charged for armed robbery in Brookfield 2/19

» Men arrested for fighting at The Cheesecake Factory 2/19

» Tosa Skatepark brick sale ending Feb. 28 2/19

» Residents face off over proposed parking structure at Wisconsin Lutheran College 2/17

» Wauwatosa Alderman Wilke ousted from county supervisor race in primary 2/17

» Wauwatosa East High School students won Scholastic Art Awards 2/17

» Two Wauwatosa students won Scholastic Writing Awards 2/17

» Explore 'The Space Race' at the Wauwatosa planetarium's upcoming program 2/17

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

2015 Writing Contest

 

(Click image for details)


Local Business Directory

CONNECT