NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
36°
H 37° L 32°
Cloudy | 16MPH

Scientist to investigate potential new targets to inhibit cancer growth

Aug. 1, 2014

The Medical College of Wisconsin (MCW) has received a two-year, $153,000 grant from the National Institute of Health’s National Cancer Institute to evaluate a potential new pathway for inhibiting the growth of cancer cells. This new pathway could lead to new diagnostic and therapeutic tools in treating malignancies.

Andrey Sorokin, Ph.D., professor of medicine in the division of nephrology at MCW, is the primary investigator of the grant.

COX-2 is an enzyme that plays a critical role in the development and spread of cancers. Currently, COX-2 inhibitors are utilized as treatments in prostate cancers and some other types of cancers. However, Dr. Sorokin’s research indicates there may be a more effective target to turn “off” the switch that allows the cancer cells to continue to grow.

In this project, Dr. Sorokin and his team will evaluate COX-2 regulation by a type of enzymes called kinases that modifies proteins by adding a phosphate group. A specific kinase called Fyn has been linked to cancer progression and will be evaluated as a novel regulator of COX-2. The project will enhance our understanding of the signaling mechanisms at a cellular level that cause cancer progression, and could provide new diagnostic tools and offer novel therapeutic targets to treat prostate cancer.

This project is supported by NIH grant R03CA182114-01A1.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Power restored to Eisenhower after classes canceled 12:56 PM

» Wauwatosa police say train death was accidental Updated:  10/30

» Photo Gallery: WIAA state soccer tourney day one 10/30

» Four-story apartment building proposed for Hall Automotive site 10/30

» Apartments planned at Hall Automotive site in Tosa Updated:  10/30

» Little Read Book in Wauwatosa has author signing Sunday 10/30

» Pedestrian struck, killed by train in Wauwatosa Updated:  10/29

» Suburban roundup: Week one of the WIAA football postseason 10/27

» New Mayfair parking structure to open tonight 10/24

» The Malt Shoppe opens Friday in Wauwatosa 10/23

» Poll: Which area team will win a state football title? 10/22

» Wauwatosa negotiating financial aid for Underwood apartments 10/22

» T.J. Maxx opening Oct. 30 in Wauwatosa 10/20

» Across Wisconsin, uneven property assessments fly in the face of fairness Updated:  10/19

» Preps football photos of the week: Week 9 10/17

» 500 free winter emergency kits given away at Mayfair tomorrow 10/17

» Camp Bar Tosa opens Saturday 10/17

» The Malt Shoppe grand opening party is Oct. 24-26 10/15

» JCPenney Furniture Outlet receives bomb threat 10/15

» Former Maharaja partner plans Indian restaurant for Wauwatosa 10/13

» New antique shop could replace Twirly Birds in Wauwatosa Village 10/13

» Preps football photos of the week: Week 8 10/10

» ID not required for voting 10/10

» Corner Bakery announces Oct. 20 opening 10/9

» Pizza Man to open second location at The Mayfair Collection 10/9

View All Posts Got a tip? Welcome rss
Deal Watch - Milwaukee

Milwaukee's Best Discounts & Deals

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

Local Business Directory

CONNECT