NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
32°
H 34° L 32°
Cloudy | 8MPH

MCW researcher to study mechanisms involved in diabetes

May 1, 2014

The Medical College of Wisconsin (MCW) has received a four-year, $1.4 million grant from the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases to study the biochemical causes of beta cell destruction in diabetes.

John A. Corbett, Ph.D., professor and chairman of biochemistry, is the principal investigator of the grant.

Autoimmune, or insulin-dependent diabetes, is characterized by an inflammatory reaction around the islets in the pancreas, and followed by destruction of beta cells. The beta cells produce insulin, which is necessary for the body to maintain and control glucose levels. When the pancreas is no longer able to produce insulin, people with diabetes must constantly test blood glucose levels and either inject insulin or ingest sugars to maintain the correct balance.

Autoimmune diabetes can also affect the heart, kidneys, blood vessels, nerves, and eyes.

In this project, Dr. Corbett’s lab will learn more about the cellular mechanisms responsible for the death of beta cells, and to identify naturally occurring mechanisms by which beta cells protect themselves against other cellular threats such as free radicals and cytokines, which are proteins that act as mediators and regulators of immune processes.

The long range goals of this project are to identify potential therapeutic strategies aimed at halting or slowing beta cell loss as a treatment or potential cure for autoimmune diabetes.

This project is funded by NIH grant R01DK052194-18A1.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Westbound I-94 near Miller Park to close for 31 hours beginning Friday night 12/18

» Woman drives drunk to pick up drunken driver from police station 12/10

» Suspects of five related burglaries in Wauwatosa arrested, charged 12/9

» Woman threatens to stab Sak's employee after retail theft 12/9

» Wauwatosa aderman runs for Milwaukee County supervisor 12/8

» Anonymous email threatens Wauwatosa East High School 12/5

» 600 bowlers, volleyball players to compete at the Special Olympics Wisconsin on Saturday 12/4

» Kindergarten registration sessions announced 12/3

» Oconomowoc man, Eisenhower teacher, dies unexpectedly 11/29

» HomeGoods coming to Mayfair Collection 11/24

» Wauwatosa superintendent attends President Barack Obama's 'ConnectED to the Future' event 11/18

» Children's Hospital of Wisconsin moves babies to newly designed NICU 11/18

» City Market closes North Avenue location 11/17

» Early momentum doesn't stay with Tosa East 11/14

» Wauwatosa woman investigated for stealing credit card information from Froedtert Hospital patients 11/13

» Man pointed handgun at front door of Applebee's 11/10

» UW Credit Union branch could break ground in Wauwatosa this month 11/10

» Suburban roundup: Week three of the WIAA football postseason 11/10

» Indulgence Chocolatiers to open in Wauwatosa, and sell Purple Door Ice Cream 11/10

» Former Central States Mortgage CEO to plead guilty to obstruction of justice Updated:  11/6

» Tosa East stuns Brookfield East in volleyball sectional 11/6

» Election roundup: How the Milwaukee suburbs and Lake Country voted Updated:  11/5

» Walker wins Wauwatosa by slimmer margin than the state 11/5

» Walker's neighbors divided over election 11/4

» Authorities identify Wauwatosa man killed by train Updated:  11/4

View All Posts Got a tip? Welcome rss

Advertisement

Deal Watch - Milwaukee

Milwaukee's Best Discounts & Deals

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

Local Business Directory

CONNECT