NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
25°
H 27° L 1°
Clear | 12MPH

MCW researcher to study mechanisms involved in diabetes

May 1, 2014

The Medical College of Wisconsin (MCW) has received a four-year, $1.4 million grant from the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases to study the biochemical causes of beta cell destruction in diabetes.

John A. Corbett, Ph.D., professor and chairman of biochemistry, is the principal investigator of the grant.

Autoimmune, or insulin-dependent diabetes, is characterized by an inflammatory reaction around the islets in the pancreas, and followed by destruction of beta cells. The beta cells produce insulin, which is necessary for the body to maintain and control glucose levels. When the pancreas is no longer able to produce insulin, people with diabetes must constantly test blood glucose levels and either inject insulin or ingest sugars to maintain the correct balance.

Autoimmune diabetes can also affect the heart, kidneys, blood vessels, nerves, and eyes.

In this project, Dr. Corbett’s lab will learn more about the cellular mechanisms responsible for the death of beta cells, and to identify naturally occurring mechanisms by which beta cells protect themselves against other cellular threats such as free radicals and cytokines, which are proteins that act as mediators and regulators of immune processes.

The long range goals of this project are to identify potential therapeutic strategies aimed at halting or slowing beta cell loss as a treatment or potential cure for autoimmune diabetes.

This project is funded by NIH grant R01DK052194-18A1.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Anthony Nash of Wauwatosa East wins EFW T-shirt design contest 02:12 PM

» Tosa Skatepark seeks graphic designer for firefly image 01:18 PM

» Menomonee River Parkway temporarily closed for excavation 3/5

» Fundraiser covers funeral expenses for victim of Wauwatosa house fire 3/5

» Carhartt coming to Wauwatosa's Mayfair Collection 3/5

» Chinese Lunar New Year celebration at Mayfair Sunday 3/4

» Police to warn against impaired driving on St. Patrick's Day 3/4

» Student in custody for bringing knives to Wauwatosa East High School 3/3

» OSHA says drill rig involved in construction worker's death Updated:  3/3

» Twirly Birds vintage store plans return to Wauwatosa 3/2

» Dry cleaner seeks expansion into old City Market in Wauwatosa 3/2

» 'Momastery' author coming to Wauwatosa 2/27

» Wauwatosa's Folley and Reagan advance to state wrestling semis 2/26

» Wauwatosa East teacher Barb Bruesewitz named ProStart Teacher of the Year 2/26

» Pancake breakfast Sunday will raise money for scholarships 2/25

» Read the winning essays in Tosa's All-City Read contest 2/24

» Victim in fatal Wauwatosa house fire was 3-year-old girl Updated:  2/23

» MMSD commission OKs $6.4 million flood control project 2/23

» Medical examiner identifies 3-year-old who died in Wauwatosa house fire 2/22

» Menomonee flood plan would free part of stream from culvert 2/20

» Five idling cars stolen in one week in Wauwatosa 2/20

» Two men attempted to defraud two Apple stores with fake iPhones 2/20

» National German Exam qualifies some students for study abroad 2/20

» Personal finance students at Wauwatosa West guess value of items in "The Twelve Days of Christmas" 2/19

» Wauwatosa woman charged for armed robbery in Brookfield 2/19

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

2015 Writing Contest

 

(Click image for details)


Local Business Directory

CONNECT