NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
16°
H ° L °
Clear | 0MPH

The role of viruses in diabetes

April 27, 2014

The Medical College of Wisconsin (MCW) has received a five-year, $1.9 million grant to study the role of viruses in pancreatic beta cell damage in diabetes.

John Corbett, Ph.D., professor and chairman of biochemistry at MCW, is the primary investigator on the grant. Dr. Corbett first began exploring the connection between viruses and beta cell death in 1999; this award paves the way for him to take the next steps in his research.

Pancreatic beta cells store and release insulin, the hormone that regulates blood sugar. In diabetes, the beta cells are destroyed and the body loses its ability to create insulin, which leads to wide swings in blood glucose levels. Autoimmune diabetes, also known as insulin-dependent diabetes, is characterized by an inflammatory reaction in the pancreas that is followed by the death of the beta cells.

Virus infection is one agent that has been suggested to cause diabetes. In this project, a mouse model will be generated to explore the role of virus infection in the induction of autoimmune diabetes. Dr. Corbett’s research team will also study the signaling pathways that are responsible for the beta cell damage in the disease.

Ultimately, by preventing the death of pancreatic beta cells, the progression of diabetes would be halted. The knowledge gleaned in this project could potentially lead to new therapeutic approaches and targets to prevent the disease.

This project is funded by NIH grant R01AI044458-15.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Wrong-way driver identified as person killed in I-94 crash 1/24

» Wauwatosa offers 'Citizen's Academy' course 1/21

» Packers playoff run prompts fond memories 1/18

» Suburban Selfies contest extended through Jan. 25; two selfie solutions to get you started! 1/15

» Wauwatosa school district adds computer science course 1/14

» Wauwatosa man dead after crash on Miller Park Way 1/12

» Wauwatosa stamp factory to become shopping center 1/12

» Mayfair Collection developer buys nearby site for retail project Updated:  1/8

» Plaque honors memory of Wauwatosa Police Officer Jennifer Sebena 1/8

» Three candidates vie to represent Wauwatosa on Milwaukee County Board 1/7

» Developers reveal plans for housing at Wauwatosa's Mayfair Collection 1/6

» Milwaukee man dead after crash in Wauwatosa 1/6

» Coast Guard member gets 5 months confinement for assault 1/6

» Friday deadline for Wauwatosa Distinguished Citizen nominations 1/5

» Wauwatosans organize rally in support of local police 1/2

» Brown's tip in makes Wauwatosa West upset winner 12/31

» Wauwatosa East to establish Athletic Hall of Fame in 2015 12/30

» Wauwatosa's All-City Read invites students, residents for essay contest 12/30

» Nordstrom to open Oct. 23, 2015 at Mayfair 12/30

» Suburban Selfies is back! Win a $200 dinner! 12/24

» Dontre Hamilton protesters rally at Bradley Center, Mayfair Updated:  12/23

» Protesters stage 'die-in' at Mayfair mall in support of Dontre Hamilton 12/23

» Westbound I-94 near Miller Park to close for 31 hours beginning Friday night 12/18

» Woman drives drunk to pick up drunken driver from police station 12/10

» Suspects of five related burglaries in Wauwatosa arrested, charged 12/9

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.


Local Business Directory

CONNECT