NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
73°
H 73° L 63°
Clear | 17MPH

Genetic Sequencing to Identify Causes of Pediatric Cataracts

Oct. 18, 2013

The Medical College of Wisconsin received a two-year, $412,500 grant from the National Institutes of Health’s National Eye Institute to study the genes associated with pediatric cataracts.

Elena V. Semina, PhD, professor of pediatrics and cell biology, neurobiology and anatomy, and an investigator at the Children’s Hospital of Wisconsin Research Institute, is the primary investigator of the grant.

While pediatric cataracts are fairly rare (between one and 15 per 10,000 births), they may interfere with normal visual development and in some cases can cause permanent blindness. Genetic studies have identified mutations in numerous genes associated with cataracts, but many cases are still awaiting molecular diagnosis.

In this project, researchers will use whole exome sequencing to identify causative mutations in both known and novel genes to facilitate characterization and classification of pediatric cataracts at a molecular level. Newly identified genes will be studied in additional patients and animal models to verify their involvement in cataract. The results of this project will provide a better understanding of eye development and will likely identify new causes of human ocular conditions like cataracts, which may lead to new diagnostic and treatment opportunities.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Preps football photos of the week: Sept. 19 9/19

» Tosa West rushes to 31-10 win over Eisenhower 9/19

» Vape Haven rejected by Wauwatosa Common Council 9/17

» Consideration overdue: Thievery marring Little Free Libraries 9/16

» Thai-namite plans fall through in East Tosa 9/15

» Preps football photos of the week: Sept. 12 9/12

» Chili'n on the Ave. is Saturday 9/12

» DSW Designer Shoe Warehouse opens tomorrow at Mayfair Collection 9/9

» TosaFest fight had no arrests or reported injuries, police say 9/9

» E-Cigarette store Vape Haven rejected by Tosa Plan Commission 9/8

» 10 Days in Tosa starts today 9/8

» 'Chaotic' scene at TosaFest limited to one area, mayor says 9/7

» Preps football photos of the week: Sept. 5 9/7

» Unruly teens disrupt Tosa Fest Updated:  9/6

» See inside Wisconsin International Academy Saturday 9/5

» Athleta coming to Mayfair 9/2

» Preps football photos of the week: Aug. 29 8/29

» Tosa West's Purifoy, big plays spark 35-15 win 8/29

» 88-year-old passenger dies after three-car crash in Tosa 8/29

» Nordstrom at Mayfair is planning a restaurant, Ruscello, and a coffee bar 8/29

» Police say train accident was 'apparent suicide' by Oak Creek man 8/28

» Milwaukee gets its first green bike lane installed in Riverwest Updated:  8/27

» Mayfair Applebee's closes after 24 years in business 8/27

» Second design workshop for Tosa skate park is Thursday 8/26

» Former Wauwatosa priest pleads not guilty to embezzlement charges 8/26

View All Posts Got a tip? Welcome rss
Deal Watch - Milwaukee

Milwaukee's Best Discounts & Deals

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

Local Business Directory

CONNECT