NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
32°
H ° L °
Cloudy | 0MPH

Genetic Sequencing to Identify Causes of Pediatric Cataracts

Oct. 18, 2013

The Medical College of Wisconsin received a two-year, $412,500 grant from the National Institutes of Health’s National Eye Institute to study the genes associated with pediatric cataracts.

Elena V. Semina, PhD, professor of pediatrics and cell biology, neurobiology and anatomy, and an investigator at the Children’s Hospital of Wisconsin Research Institute, is the primary investigator of the grant.

While pediatric cataracts are fairly rare (between one and 15 per 10,000 births), they may interfere with normal visual development and in some cases can cause permanent blindness. Genetic studies have identified mutations in numerous genes associated with cataracts, but many cases are still awaiting molecular diagnosis.

In this project, researchers will use whole exome sequencing to identify causative mutations in both known and novel genes to facilitate characterization and classification of pediatric cataracts at a molecular level. Newly identified genes will be studied in additional patients and animal models to verify their involvement in cataract. The results of this project will provide a better understanding of eye development and will likely identify new causes of human ocular conditions like cataracts, which may lead to new diagnostic and treatment opportunities.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Meijer to open Wauwatosa store in August 1/28

» Wauwatosa committee recommends e-cigarette restrictions 1/28

» Two businesses in same building burglarized 1/27

» Wrong-way driver identified as person killed in I-94 crash 1/24

» Wauwatosa offers 'Citizen's Academy' course 1/21

» Packers playoff run prompts fond memories 1/18

» Suburban Selfies contest extended through Jan. 25; two selfie solutions to get you started! 1/15

» Wauwatosa school district adds computer science course 1/14

» Wauwatosa man dead after crash on Miller Park Way 1/12

» Wauwatosa stamp factory to become shopping center 1/12

» Mayfair Collection developer buys nearby site for retail project Updated:  1/8

» Three candidates vie to represent Wauwatosa on Milwaukee County Board 1/7

» Developers reveal plans for housing at Wauwatosa's Mayfair Collection 1/6

» Milwaukee man dead after crash in Wauwatosa 1/6

» Coast Guard member gets 5 months confinement for assault 1/6

» Friday deadline for Wauwatosa Distinguished Citizen nominations 1/5

» Wauwatosans organize rally in support of local police 1/2

» Brown's tip in makes Wauwatosa West upset winner 12/31

» Wauwatosa East to establish Athletic Hall of Fame in 2015 12/30

» Wauwatosa's All-City Read invites students, residents for essay contest 12/30

» Nordstrom to open Oct. 23, 2015 at Mayfair 12/30

» Suburban Selfies is back! Win a $200 dinner! 12/24

» Dontre Hamilton protesters rally at Bradley Center, Mayfair Updated:  12/23

» Protesters stage 'die-in' at Mayfair mall in support of Dontre Hamilton 12/23

» Westbound I-94 near Miller Park to close for 31 hours beginning Friday night 12/18

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.


Local Business Directory

CONNECT