NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
27°
H 30° L 19°
Cloudy | 0MPH

Genetic Sequencing to Identify Causes of Pediatric Cataracts

Oct. 18, 2013

The Medical College of Wisconsin received a two-year, $412,500 grant from the National Institutes of Health’s National Eye Institute to study the genes associated with pediatric cataracts.

Elena V. Semina, PhD, professor of pediatrics and cell biology, neurobiology and anatomy, and an investigator at the Children’s Hospital of Wisconsin Research Institute, is the primary investigator of the grant.

While pediatric cataracts are fairly rare (between one and 15 per 10,000 births), they may interfere with normal visual development and in some cases can cause permanent blindness. Genetic studies have identified mutations in numerous genes associated with cataracts, but many cases are still awaiting molecular diagnosis.

In this project, researchers will use whole exome sequencing to identify causative mutations in both known and novel genes to facilitate characterization and classification of pediatric cataracts at a molecular level. Newly identified genes will be studied in additional patients and animal models to verify their involvement in cataract. The results of this project will provide a better understanding of eye development and will likely identify new causes of human ocular conditions like cataracts, which may lead to new diagnostic and treatment opportunities.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Westbound I-94 near Miller Park to close for 31 hours beginning Friday night 12/18

» Woman drives drunk to pick up drunken driver from police station 12/10

» Suspects of five related burglaries in Wauwatosa arrested, charged 12/9

» Woman threatens to stab Sak's employee after retail theft 12/9

» Wauwatosa aderman runs for Milwaukee County supervisor 12/8

» Anonymous email threatens Wauwatosa East High School 12/5

» 600 bowlers, volleyball players to compete at the Special Olympics Wisconsin on Saturday 12/4

» Kindergarten registration sessions announced 12/3

» Oconomowoc man, Eisenhower teacher, dies unexpectedly 11/29

» HomeGoods coming to Mayfair Collection 11/24

» Wauwatosa superintendent attends President Barack Obama's 'ConnectED to the Future' event 11/18

» Children's Hospital of Wisconsin moves babies to newly designed NICU 11/18

» City Market closes North Avenue location 11/17

» Early momentum doesn't stay with Tosa East 11/14

» Wauwatosa woman investigated for stealing credit card information from Froedtert Hospital patients 11/13

» Man pointed handgun at front door of Applebee's 11/10

» UW Credit Union branch could break ground in Wauwatosa this month 11/10

» Suburban roundup: Week three of the WIAA football postseason 11/10

» Indulgence Chocolatiers to open in Wauwatosa, and sell Purple Door Ice Cream 11/10

» Former Central States Mortgage CEO to plead guilty to obstruction of justice Updated:  11/6

» Tosa East stuns Brookfield East in volleyball sectional 11/6

» Election roundup: How the Milwaukee suburbs and Lake Country voted Updated:  11/5

» Walker wins Wauwatosa by slimmer margin than the state 11/5

» Walker's neighbors divided over election 11/4

» Authorities identify Wauwatosa man killed by train Updated:  11/4

View All Posts Got a tip? Welcome rss

Advertisement

Deal Watch - Milwaukee

Milwaukee's Best Discounts & Deals

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

Local Business Directory

CONNECT