Understanding the Eye: Researchers to Explore Vision at the Cellular Level

Sept. 9, 2013

The Medical College of Wisconsin (MCW) has received a four-year, $2 million grant from the National Institutes of Health’s National Eye Institute to study the causes and progression of eye diseases at the cellular level.

Joseph Carroll, PhD, associate professor of ophthalmology, biophysics, and cell biology, neurobiology and anatomy, is the principal investigator of the grant. Dr. Carroll is also the co-director of the Advanced Ocular Imaging Program (AOIP) at the Froedtert & Medical College Eye Institute. Co-investigators on the multi-center project include Thomas Connor, Jr., MD, and Kimberly E. Stepien, MD, associate professors of ophthalmology at MCW; and Alfredo Dubra, PhD, assistant professor of ophthalmology and Co-Director of the AOIP; Michel Michaelides, MBBS, University College London; and Pei-wen Chiang, PhD, Oregon Health & Science University.

Inherited retinal degenerations affect approximately one in 1,500 individuals in the United States, and the prospect of treating these devastating diseases has been a daunting task for clinicians. While progress has been made in the development of therapeutic strategies for these conditions in animal models, sensitive tools to directly and immediately assess how various interventions might affect retinal health in human patients do not exist.

In this project, researchers will to develop sensitive, noninvasive, cellular-resolution techniques for assessing photoreceptor structure in the living human retina. In addition, they will utilize genetic analysis and electrophysiological and behavioral testing to investigate how cellular disruptions in the retina affect visual function. Insights gleaned from that study will accelerate the application of this high-resolution imaging approach to define therapeutic potential on an individualized basis and to provide anatomical outcome measures for use in emerging therapeutic trials.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Wauwatosa West boys basketball team defeats Shorewood, South Milwaukee 2/3

» Marquette gets revenge with 75-55 victory over Wauwatosa East boys 2/3

» Wauwatosa East's Stewart, Green combine for 49 points in win over Brookfield Central 2/3

» Wauwatosa West girls basketball team loses road games to Shorewood, South Milwaukee 2/3

» Wauwatosa Hurricanes finish second at Bob White Swimming Invitational 2/3

» Wauwatosa Tosa girls basketball team drops tough decisions to Lancers, Chargers 2/3

» Pewaukee whips Wauwatosa wrestlers to take first in conference 2/3

» Updated rankings of area prep boys and girls basketball teams and players 2/1

» Positive and uplifting stories in suburban Milwaukee and Lake Country in January 2/1

» Eastbound Blue Mound Road reopens in Wauwatosa Updated:  1/29

» Video: Tosa Top 5: Five things you need to know in Wauwatosa this week 1/28

» Milwaukee Co. launches coyote tracking program in Tosa, West Allis 1/28

» Wauwatosa wrestlers beat South Milwaukee, take third in Janssen Invite 1/27

» Bailey Berlin's free throws give Wauwatosa East win over Tosa West 1/27

» Wauwatosa East girls nip Brookfield East, 52-51, for big GMC victory 1/27

» Wauwatosa West girls basketball team beats Greenfield, snaps 8-game losing streak 1/27

» Wauwatosa Hurricanes sweep St. Thomas More/St. Francis, 144-30 1/27

» Wauwatosa West boys basketball team crushes Greenfield, 76-45 1/27

» Fun-loving Shorewood girls basketball team routs Tosa West, 60-34 1/26

» Tosa's All-City Read kicks off in early February, more events coming 1/26

» Second Wauwatosa business saved from fire damage thanks to sprinkler system 1/25

» Wauwatosa man under investigation for illegal gun sales Updated:  1/25

» Gov. Scott Walker's Wauwatosa home for sale 1/25

» Wauwatosa water main break causes geyser-like effect in Village 1/22

» Screaming Tuna gets nod of approval from Wauwatosa Common Council Updated:  1/22

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporters Rory Linnane or Rachel Minske explore the closed down and closed off parts of Wauwatosa.

Advertisement

Local Business Directory

CONNECT