The Medical College of Wisconsin has received a $1.45 million grant from the National Institutes of Health’s Heart, Lung, and Blood Institutes supporting research investigating the neural control of respiration.
Hubert V. Forster, Ph.D., professor of physiology, is the primary investigator of the grant. In this project, he will study the mechanisms by which the brain regulates breathing. Orchestration of the release and metabolism of multiple neurochemicals is crucial in this regulation, but how this occurs remains poorly understood. His laboratory studies the ways in which neurochemicals interact under normal conditions, and how these interactions become dysfunctional in conditions such as sleep apnea or during opioid administration.
During sleep, breathing is reduced. Researchers believe this is due to natural fluctuations in neurochemicals that normally stimulate breathing. This potentially vulnerable respiratory state may underlie the depressive effects on breathing of clinical or recreational opioid use, and the development of sleep-disordered breathing (SDB) and obstructive sleep apnea (OSA). SDB and OSA have become increasingly prevalent among American adults and are associated with conditions such as hypertension.
Objectives of the grant include understanding the pathology of SDB and OSA, and the respiratory effects of opioids at the whole animal and neurochemical level. A long-term goal of these studies is to provide insight on the prevention and management of these conditions
Your link to the biggest stories in the suburbs delivered Thursday mornings.
Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter Get the Newsletter!
- Callen Receives 2015 Pulse of the City Customer Service Award
- MCW to host renowned nutrition expert at heart health conference
- Greater Brookfield Chamber of Commerce presents Bluemound Road Building Boom – From Barker to Moorland
- Time to Brush Up
- Independent Business Association of Wisconsin (IBAW) to host Preparing Future Generations for Career Readiness
- Metallurgical Associates Announces New/Old Ownership
- Black Lives Matter: Racial Disparity and the Criminal Justice System
- Milwaukee NARI Foundation Announces 2016 Spring Semester Scholarship Recipients
- Wauwatosa West Dance Team wins Regionals
- Bartelt Wins 2016 Regional Contractor of the Year (CotY) Award