Our privacy policy has changed. By using this site, you agree to the Privacy Policy and Terms of Use. Dismiss

How the Brain Regulates Breathing

Aug. 24, 2013

The Medical College of Wisconsin has received a $1.45 million grant from the National Institutes of Health’s Heart, Lung, and Blood Institutes supporting research investigating the neural control of respiration.
Hubert V. Forster, Ph.D., professor of physiology, is the primary investigator of the grant. In this project, he will study the mechanisms by which the brain regulates breathing. Orchestration of the release and metabolism of multiple neurochemicals is crucial in this regulation, but how this occurs remains poorly understood. His laboratory studies the ways in which neurochemicals interact under normal conditions, and how these interactions become dysfunctional in conditions such as sleep apnea or during opioid administration.
During sleep, breathing is reduced. Researchers believe this is due to natural fluctuations in neurochemicals that normally stimulate breathing. This potentially vulnerable respiratory state may underlie the depressive effects on breathing of clinical or recreational opioid use, and the development of sleep-disordered breathing (SDB) and obstructive sleep apnea (OSA). SDB and OSA have become increasingly prevalent among American adults and are associated with conditions such as hypertension.
Objectives of the grant include understanding the pathology of SDB and OSA, and the respiratory effects of opioids at the whole animal and neurochemical level. A long-term goal of these studies is to provide insight on the prevention and management of these conditions

Community Watch

» With peers downsizing, couple takes on ultimate fixer-upper 5/28

» Name revealed of new female giraffe at Milwaukee Co. Zoo 5/26

» Wauwatosa law enforcement honors fallen officers during national bike tour Updated:  5/26

» Tosa Top 5: Five things you need to know about in Wauwatosa this week 5/25

» Wauwatosa West boys finish fourth at Woodland Relays 5/25

» Wauwatosa West girls soccer team wins Woodland Conference championship 5/25

» Wauwatosa East soccer team splits two games, loses Lily Brock to injury 5/25

» Wauwatosa East girls finish seventh at GMC Outdoor Track and Field Meet 5/25

» Wauwatosa East boys fourth at GMC Outdoor Track and Field Meet 5/25

» State Street road work may be the biggest headache this year in Wauwatosa 5/25

» Wauwatosa Sports Notes: May 26, 2016 5/24

» Milwaukee County Chargers defeat Bulldogs in exhibition opener, 20-6 5/24

» Wauwatosa officer rescues seven ducklings trapped in storm sewer 5/24

» Initial Reaction: Talking with star Waukesha soccer players Dani Rhodes, Emily Cervantes Updated:  5/24

» Wauwatosa Police Report: May 15 - 21 5/24

» Wauwatosa West girls track team runs away with Woodland Outdoor title 5/24

» Video: Reporter takes us along the 2016 Run Tosa Run 5/23

» Tosa Top 5: Five things you need to know about in Wauwatosa this week 5/20

» Suspects charged in string of armed robberies through Wauwatosa, Milwaukee Updated:  5/19

» New Mayfair GM announces plans for a Z Gallerie furniture store Updated:  5/18

» Wauwatosa East baseball team will rely on defense, depth in 2016 5/18

» Wauwatosa East softball teams beats West Allis Central in twinbill 5/18

» Campus News: May 19 5/18

» Sports Shorts: May 19, 2016 5/18

» Wauwatosa East girls soccer team crushes West Allis Central, 11-0 5/18

View All Posts Got a tip? Welcome rss

Best Summer Ever

 

We've made it easy for you to get out and go this summer. From hitting the trails for a bike ride or walk, to where to find beer gardens in the area, to the best places to swim in Waukesha County to the best summer drinks and summer reads, check out our 2016 summer guide.

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where our Wauwatosa reporter explores the closed down and closed off parts of Wauwatosa.

Advertisement

CONNECT