NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
52°
H 64° L 52°
Rain | 9MPH

MCW Researcher to Study Infectious Cycle of Polioviruses

July 26, 2013

The Medical College of Wisconsin (MCW) has received a one year, $360,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to study the ways in which polioviruses replicate and become infectious.

William Jackson, PhD, assistant professor of microbiology and molecular genetics at MCW, is the primary investigator of the grant.

Poliovirus is a member of a group of viruses called picornaviridae, which also includes common human viruses such as coxsackievirus, which causes hand, foot and mouth disease, and and rhinovirus, the primary agent of the common cold. This class of viruses also includes foot and mouth disease virus, which is devastating to cattle herds. The different viruses in the group appear to replicate in the same way, and the methods of replication are not fully understood.

In this project, Dr. Jackson will study tiny bubbles of membranes, called vesicles, in cells infected with poliovirus. An infected cell quickly fills with vesicles, which are believed to then become acidic, creating an environment which helps the virus change into its infectious form. By studying the nature of the vesicles and the way in which infection promotes their development, researchers will learn how this medically important family of viruses subverts cellular pathways to replicate itself. This will provide information to ultimately help identify therapeutic targets that may ultimately lead to treatments against multiple viral diseases.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Research Park leadership changing with Drew's retirement 5/29

» Monarch-friendly plants for sale in Wauwatosa Sunday 5/29

» Milwaukee man charged for causing fatal rollover crash in Wauwatosa 5/28

» Run Tosa Run raises $3K for Ronald McDonald House 5/26

» Longfellow hosting Wauwatosa's Memorial Day ceremony Monday 5/21

» Choice school, dry cleaning issues held for more discussion in Wauwatosa 5/20

» Parents rally after lawmakers expand vouchers 5/20

» Wauwatosa approves conceptual design for pocket park on North Avenue Updated:  5/20

» Wauwatosa hotel site sells for $925,000 5/20

» Tosa Tonight releases lineup for summer concert series 5/19

» Wauwatosa School Board approves raises for teachers, administrators and staff 5/19

» Wauwatosa Avenue lane to close over Memorial Day weekend 5/18

» Residents invited to help redesign streets, parks in Wauwatosa Village 5/15

» Wauwatosa alderman pulls proposal to shrink common council 5/15

» Police arrest teens for prowling after foot chase through Wauwatosa Updated:  5/14

» Initial Reaction Podcast: Massive overhaul of area conferences could be afoot 5/13

» Beer garden at Hoyt Park in Tosa reopens Wednesday, may go indoors too 5/12

» Winter's not through with us yet 5/12

» Wauwatosa mayor named to MMSD governing commission 5/11

» Police say motorcyclist riding without helmet injured in Wauwatosa collision 5/7

» Ex-Wauwatosa school board vice president 'disheartened by political dissonance' in community Updated:  5/6

» Wauwatosa celebrating Bike to School Day Wednesday 5/5

» Wauwatosa alderman proposes cutting four seats on Common Council 5/4

» East kickers blank Tosa West, 2-0 5/2

» Investigation: Family behind collapsed Falls building has a history of neglecting properties Updated:  5/1

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

2015 Writing Contest

 

(Click image for details)

Local Business Directory

CONNECT