NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
25°
H 25° L 25°
Cloudy | 13MPH

MCW Researcher to Study Infectious Cycle of Polioviruses

July 26, 2013

The Medical College of Wisconsin (MCW) has received a one year, $360,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to study the ways in which polioviruses replicate and become infectious.

William Jackson, PhD, assistant professor of microbiology and molecular genetics at MCW, is the primary investigator of the grant.

Poliovirus is a member of a group of viruses called picornaviridae, which also includes common human viruses such as coxsackievirus, which causes hand, foot and mouth disease, and and rhinovirus, the primary agent of the common cold. This class of viruses also includes foot and mouth disease virus, which is devastating to cattle herds. The different viruses in the group appear to replicate in the same way, and the methods of replication are not fully understood.

In this project, Dr. Jackson will study tiny bubbles of membranes, called vesicles, in cells infected with poliovirus. An infected cell quickly fills with vesicles, which are believed to then become acidic, creating an environment which helps the virus change into its infectious form. By studying the nature of the vesicles and the way in which infection promotes their development, researchers will learn how this medically important family of viruses subverts cellular pathways to replicate itself. This will provide information to ultimately help identify therapeutic targets that may ultimately lead to treatments against multiple viral diseases.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Wauwatosa Senior Commission surveying seniors 1/29

» Answers and winners of the Suburban Selfies contest revealed! 1/29

» Four similar thefts reported at Wisconsin Lutheran College 1/29

» Meijer to open Wauwatosa store in August 1/28

» Wauwatosa committee recommends e-cigarette restrictions 1/28

» Two businesses in same building burglarized 1/27

» Wrong-way driver identified as person killed in I-94 crash 1/24

» Wauwatosa offers 'Citizen's Academy' course 1/21

» Packers playoff run prompts fond memories 1/18

» Suburban Selfies contest extended through Jan. 25; two selfie solutions to get you started! 1/15

» Wauwatosa school district adds computer science course 1/14

» Wauwatosa man dead after crash on Miller Park Way 1/12

» Wauwatosa stamp factory to become shopping center 1/12

» Mayfair Collection developer buys nearby site for retail project Updated:  1/8

» Three candidates vie to represent Wauwatosa on Milwaukee County Board 1/7

» Developers reveal plans for housing at Wauwatosa's Mayfair Collection 1/6

» Milwaukee man dead after crash in Wauwatosa 1/6

» Coast Guard member gets 5 months confinement for assault 1/6

» Friday deadline for Wauwatosa Distinguished Citizen nominations 1/5

» Wauwatosans organize rally in support of local police 1/2

» Brown's tip in makes Wauwatosa West upset winner 12/31

» Wauwatosa East to establish Athletic Hall of Fame in 2015 12/30

» Wauwatosa's All-City Read invites students, residents for essay contest 12/30

» Nordstrom to open Oct. 23, 2015 at Mayfair 12/30

» Suburban Selfies is back! Win a $200 dinner! 12/24

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.


Local Business Directory

CONNECT