NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
64°
H 64° L 52°
Light Rain | 0MPH

MCW Researcher to Study Key Bacterial Toxin

July 19, 2013

The Medical College of Wisconsin (MCW) has received a five year, $1.5 million grant from the National Institute of Health’s National Institute of Allergy and Infectious Diseases to study the pathogenesis of Pseudomonas aeruginosa, a bacterium that is intrinsically resistant to antimicrobials, and that is difficult to treat.

Dara Frank, PhD, professor of microbiology and molecular genetics and director of MCW’s Center for Infectious Disease Research, is the primary investigator of the grant. Jimmy Feix, PhD, professor of biophysics, is a co-investigator.

Pseudomonas aeruginosa has been linked to burn victims, immunocompromised patients, and individuals with cystic fibrosis. Colonization of organs such as the lungs or spread of the bacteria to the bloodstream, can result in a fatal infection. Toxins expressed by the bacteria make it particularly pathogenic.

In this study, Dr. Frank will study a toxin expressed by Pseudomonas aeruginosa called ExoU, which is correlated with poor outcomes in human infection. By studying ExoU and the system in which it is expressed, new insights about the pathogenic nature of the bacteria will be discovered, with the ultimate goal being to provide unique targets and biological tools to limit that pathogenicity—and improve outcomes in human infections.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Longfellow hosting Wauwatosa's Memorial Day ceremony Monday 5/21

» Choice school, dry cleaning issues held for more discussion in Wauwatosa 5/20

» Parents rally after lawmakers expand vouchers 5/20

» Wauwatosa approves conceptual design for pocket park on North Avenue Updated:  5/20

» Wauwatosa hotel site sells for $925,000 5/20

» Tosa Tonight releases lineup for summer concert series 5/19

» Wauwatosa School Board approves raises for teachers, administrators and staff 5/19

» Wauwatosa Avenue lane to close over Memorial Day weekend 5/18

» Residents invited to help redesign streets, parks in Wauwatosa Village 5/15

» Wauwatosa alderman pulls proposal to shrink common council 5/15

» Police arrest teens for prowling after foot chase through Wauwatosa Updated:  5/14

» Initial Reaction Podcast: Massive overhaul of area conferences could be afoot 5/13

» Beer garden at Hoyt Park in Tosa reopens Wednesday, may go indoors too 5/12

» Winter's not through with us yet 5/12

» Wauwatosa mayor named to MMSD governing commission 5/11

» Police say motorcyclist riding without helmet injured in Wauwatosa collision 5/7

» Ex-Wauwatosa school board vice president 'disheartened by political dissonance' in community Updated:  5/6

» Wauwatosa celebrating Bike to School Day Wednesday 5/5

» Wauwatosa alderman proposes cutting four seats on Common Council 5/4

» East kickers blank Tosa West, 2-0 5/2

» Investigation: Family behind collapsed Falls building has a history of neglecting properties Updated:  5/1

» Wauwatosa's Lady in Red reopens as Nikki's Boutique after remodel 4/30

» Exactly 175 years ago, Wauwatosa became a town 4/30

» Tosa Recreation Dept. to hold textile recycling event 4/29

» Wauwatosa parents ask Sen. Leah Vukmir to increase education funding 4/27

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

2015 Writing Contest

 

(Click image for details)

Local Business Directory

CONNECT