MCW Researcher to Study Key Bacterial Toxin

July 19, 2013

The Medical College of Wisconsin (MCW) has received a five year, $1.5 million grant from the National Institute of Health’s National Institute of Allergy and Infectious Diseases to study the pathogenesis of Pseudomonas aeruginosa, a bacterium that is intrinsically resistant to antimicrobials, and that is difficult to treat.

Dara Frank, PhD, professor of microbiology and molecular genetics and director of MCW’s Center for Infectious Disease Research, is the primary investigator of the grant. Jimmy Feix, PhD, professor of biophysics, is a co-investigator.

Pseudomonas aeruginosa has been linked to burn victims, immunocompromised patients, and individuals with cystic fibrosis. Colonization of organs such as the lungs or spread of the bacteria to the bloodstream, can result in a fatal infection. Toxins expressed by the bacteria make it particularly pathogenic.

In this study, Dr. Frank will study a toxin expressed by Pseudomonas aeruginosa called ExoU, which is correlated with poor outcomes in human infection. By studying ExoU and the system in which it is expressed, new insights about the pathogenic nature of the bacteria will be discovered, with the ultimate goal being to provide unique targets and biological tools to limit that pathogenicity—and improve outcomes in human infections.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Tosa officers return to work following police-involved shooting 03:35 PM

» Fat Tuesday: How Wauwatosa celebrated 02:28 PM

» As trial begins, man pleads guilty to shooting Wauwatosa police officer Updated:  2/8

» Tosa's All-City Read well underway, more events to come 2/8

» Wauwatosa Revolving Loan Fund celebrates 25 years 2/8

» Milwaukee Co. Zoo welcomes two new lionesses 2/8

» Updated rankings of area prep boys and girls basketball teams and players 2/8

» Wauwatosa West boys basketball team defeats Shorewood, South Milwaukee 2/3

» Marquette gets revenge with 75-55 victory over Wauwatosa East boys 2/3

» Wauwatosa East's Stewart, Green combine for 49 points in win over Brookfield Central 2/3

» Wauwatosa West girls basketball team loses road games to Shorewood, South Milwaukee 2/3

» Wauwatosa Hurricanes finish second at Bob White Swimming Invitational 2/3

» Wauwatosa Tosa girls basketball team drops tough decisions to Lancers, Chargers 2/3

» Pewaukee whips Wauwatosa wrestlers to take first in conference 2/3

» Positive and uplifting stories in suburban Milwaukee and Lake Country in January 2/1

» Eastbound Blue Mound Road reopens in Wauwatosa Updated:  1/29

» Video: Tosa Top 5: Five things you need to know in Wauwatosa this week 1/28

» Milwaukee Co. launches coyote tracking program in Tosa, West Allis 1/28

» Wauwatosa wrestlers beat South Milwaukee, take third in Janssen Invite 1/27

» Bailey Berlin's free throws give Wauwatosa East win over Tosa West 1/27

» Wauwatosa East girls nip Brookfield East, 52-51, for big GMC victory 1/27

» Wauwatosa West girls basketball team beats Greenfield, snaps 8-game losing streak 1/27

» Wauwatosa Hurricanes sweep St. Thomas More/St. Francis, 144-30 1/27

» Wauwatosa West boys basketball team crushes Greenfield, 76-45 1/27

» Fun-loving Shorewood girls basketball team routs Tosa West, 60-34 1/26

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporters Rory Linnane or Rachel Minske explore the closed down and closed off parts of Wauwatosa.

Advertisement

Election center 2016

Election overage from from the MyCommunityNow coverage area covering suburban Milwaukee County and the eastern half of Waukesha County.

Suburban Milwaukee election center 2016

Local Business Directory

CONNECT