H 43° L 41°
Clear | 0MPH

Predicting Type 1 Diabetes at a Molecular Level

May 3, 2013

The Medical College of Wisconsin and Children’s Hospital of Wisconsin Research Institute received a three-year, $857,000 grant from the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases to continue to develop an assay shown to detect inflammation linked to the development of Type 1 diabetes (T1D) before patients are symptomatic.

Martin J. Hessner, Ph.D., professor of pediatrics, investigator at the Children’s Hospital of Wisconsin Research Institute, and director of the Max McGee National Research Center for Juvenile Diabetes at Children’s Hospital, is the primary investigator. Carla J. Greenbaum, M.D., director of the diabetes research program at the Benaroya Research Institute at Virginia Mason Medical Center in Seattle, is co-primary investigator.

Many inflammatory diseases, including T1D, become evident only after tissue damage has progressed and patients show signs of illness.

The researchers have developed a bioassay that measures a T1D signature that indicates early signs of inflammation. In all cases studied in which patients developed T1D, the signature was evident prior to disease onset. In this study, the research team aims to define that signature as a quantitative early biomarker to stage the disease, and also to define disease-specificity of the signature for T1D.

This project could potentially lead to new technological developments that would help predict T1D in patients before the onset of symptoms, which would allow for earlier intervention and preservation of pancreatic function.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.

Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Thousands of items on sale at Wauwatosa Public Library in late October 10/9

» Wauwatosa School District to host 'Autism Insights and Strategies' 10/9

» Updated week eight rankings of area prep football teams and players 10/9

» Public invited to name baby giraffe at Milwaukee Co. Zoo 10/9

» Large crowd in Wauwatosa gymnasium discusses coyote attacks, seeks answers Updated:  10/8

» Wauwatosa West girls volleyball team bounces back for victory 10/7

» Wauwatosa East volleyball team wins thriller against Trojans 10/7

» Wauwatosa East soccer team ties second-ranked Cedarburg 10/7

» Wauwatosa West football team blanks Vikings, earns playoff spot 10/7

» Wauwatosa East boys cross country team finished second at the Purgold Invite 10/7

» Wauwatosa East boys volleyball team beats Cedarburg 10/7

» Wauwatosa East, West girls cross-country teams finish third, fourth at Purgold Invitational 10/7

» Wauwatosa West girls tennis finishes second in Woodland Tennis Tournament 10/7

» Public invited to Wauwatosa Village streetscape workshop 10/6

» Bedbugs found in Wauwatosa juvenile court center Updated:  10/6

» Nordstrom Mayfair announces gala, late-night party fundraising events 10/6

» Aurora plans $35 million upgrade to psychiatric hospital in Tosa Updated:  10/2

» Mayfair mall, Susan G. Komen host series of breast cancer events 10/2

» Wauwatosa schools celebrate Walk to School Day on Oct. 7 10/2

» Initial Reaction Podcast: Is Aaron Rodgers really the best QB in football? 10/1

» Wauwatosa West football whips Pius XI in wild scoring affair 9/29

» Tosa West boys split two matches 9/29

» East kickers tie, lose, win during busy week 9/29

» Tosa East girls take third at Bay Invitational 9/29

» East's Potter finishes second at Nikolai Invite 9/29

View All Posts Got a tip? Welcome rss



Hidden Tosa


"Hidden Tosa" is a semi-regular feature where reporters Rory Linnane or Rachel Minske explore the closed down and closed off parts of Wauwatosa.


Local Business Directory