Our privacy policy has changed. By using this site, you agree to the Privacy Policy and Terms of Use. Dismiss

Predicting Type 1 Diabetes at a Molecular Level

May 3, 2013

The Medical College of Wisconsin and Children’s Hospital of Wisconsin Research Institute received a three-year, $857,000 grant from the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases to continue to develop an assay shown to detect inflammation linked to the development of Type 1 diabetes (T1D) before patients are symptomatic.

Martin J. Hessner, Ph.D., professor of pediatrics, investigator at the Children’s Hospital of Wisconsin Research Institute, and director of the Max McGee National Research Center for Juvenile Diabetes at Children’s Hospital, is the primary investigator. Carla J. Greenbaum, M.D., director of the diabetes research program at the Benaroya Research Institute at Virginia Mason Medical Center in Seattle, is co-primary investigator.

Many inflammatory diseases, including T1D, become evident only after tissue damage has progressed and patients show signs of illness.

The researchers have developed a bioassay that measures a T1D signature that indicates early signs of inflammation. In all cases studied in which patients developed T1D, the signature was evident prior to disease onset. In this study, the research team aims to define that signature as a quantitative early biomarker to stage the disease, and also to define disease-specificity of the signature for T1D.

This project could potentially lead to new technological developments that would help predict T1D in patients before the onset of symptoms, which would allow for earlier intervention and preservation of pancreatic function.

Community Watch

» Shoulder mount of beloved deer 'Bow Tie' to return to Milwaukee Co. Parks 5/5

» Video Tosa Top 5: Five things you need to know about in Wauwatosa this week 5/5

» Sports Shorts: May 5, 2016 5/4

» Wauwatosa East batters come to life against Brown Deer, Brookfield East 5/4

» Wauwatosa East boys track team finishes fourth at Dan Benson Invite 5/4

» Wauwatosa golfers win Panther Invite 5/4

» Wauwatosa West softball team holds on to nip Port Washington 5/4

» Wauwatosa East girls track team finishes fourth at Dan Benson Invite 5/4

» Adams leads the way for Wauwatosa West girls at Dan Benson Invite 5/4

» Wauwatosa West boys track and field team finishes fifth at Dan Benson Invite 5/4

» Initial Reaction Podcast: Schobert, Watt, Packers and social media foibles of NFL Draft 5/2

» Travis Hudson earns third straight volleyball National Player of the Year Award 5/2

» Wauwatosa East student named 2016 presidential scholar 5/2

» Tosa Tonight announces 2016 concert headliners 5/2

» 360NOW: Wander Wawatosa's village 4/29

» Milwaukee Co. Zoo welcomes new female giraffe calf 4/29

» Video Tosa Top 5: Five things you need to know about in Wauwatosa 4/28

» Wauwatosa seeks volunteers for focus groups on city communication 4/28

» Show about solitary confinement encourages discussion, activism 4/28

» Annual Tosa Night Out celebration will relocate to Milwaukee County Zoo Updated:  4/27

» District leaders question use of Wauwatosa schools as voting locations Updated:  4/27

» Area businesses collaborate to create the 'Cranky Sammie' in East Tosa 4/27

» Wauwatosa Sports Notes: Players sign with colleges, baseball fundraiser, more 4/26

» Wauwatosa West sprinters stand out at Kansas Relays 4/26

» Wauwatosa West' Hannah-Howell, Jefferson shine at Sun Prairie Track Meet 4/26

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where our Wauwatosa reporter explores the closed down and closed off parts of Wauwatosa.

Advertisement

CONNECT