NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
21°
H 21° L 12°
Clear | 7MPH

MCW Researcher to Study Evasive Immune Strategies of Herpesviruses

March 20, 2013

The Medical College of Wisconsin has received a two-year, $476,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to study immune response to certain herpesviruses.

Amy W. Hudson, PhD, associate professor of microbiology and molecular genetics, is the primary investigator of the grant.

Human herpesviruses -6 and -7 infect essentially the world’s entire population before the age of five. Like all herpesviruses, these viruses remain latent or persistent throughout life. HHV-6 and -7 (Roseoloviruses) are common childhood illnesses. In most children, infection with HHV -6 or -7 causes a fever, which can be quite high; in some cases, these high fevers cause seizures. Recent studies suggest that these febrile seizures are associated with increased risk of developing epilepsy later in life.

Since herpesviruses remain latent or persistent within us throughout life, they must necessarily excel at escaping immune detection throughout the life of the host. Because HHV-6 and -7 infect only humans, an animal model in which to study how these viruses interact with and thwart immune detection does not exist.

In this project, Dr. Hudson will develop a mouse model with a “humanized” immune system to study the mechanisms by which these viruses evade detection by the immune system. This will lead to a better understanding of acute and latent infection, and may have future clinical application in the treatment of epilepsy and autoimmune disorders.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Dry cleaner seeks expansion into old City Market in Wauwatosa 08:15 AM

» Twirly Birds vintage store plans return to Wauwatosa 08:00 AM

» Construction worker dies in machinery accident at Zoo Interchange project 2/28

» 'Momastery' author coming to Wauwatosa 2/27

» Wauwatosa's Folley and Reagan advance to state wrestling semis 2/26

» Wauwatosa East teacher Barb Bruesewitz named ProStart Teacher of the Year 2/26

» Pancake breakfast Sunday will raise money for scholarships 2/25

» Read the winning essays in Tosa's All-City Read contest 2/24

» Victim in fatal Wauwatosa house fire was 3-year-old girl Updated:  2/23

» MMSD commission OKs $6.4 million flood control project 2/23

» Medical examiner identifies 3-year-old who died in Wauwatosa house fire 2/22

» Menomonee flood plan would free part of stream from culvert 2/20

» Five idling cars stolen in one week in Wauwatosa 2/20

» Two men attempted to defraud two Apple stores with fake iPhones 2/20

» National German Exam qualifies some students for study abroad 2/20

» Personal finance students at Wauwatosa West guess value of items in "The Twelve Days of Christmas" 2/19

» Wauwatosa woman charged for armed robbery in Brookfield 2/19

» Men arrested for fighting at The Cheesecake Factory 2/19

» Tosa Skatepark brick sale ending Feb. 28 2/19

» Residents face off over proposed parking structure at Wisconsin Lutheran College 2/17

» Wauwatosa Alderman Wilke ousted from county supervisor race in primary 2/17

» Wauwatosa East High School students won Scholastic Art Awards 2/17

» Two Wauwatosa students won Scholastic Writing Awards 2/17

» Explore 'The Space Race' at the Wauwatosa planetarium's upcoming program 2/17

» Protesters march on Scott Walker's Wauwatosa home to decry state budget cuts Updated:  2/16

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.


Local Business Directory

CONNECT