NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
45°
H 45° L 43°
Light Rain | 5MPH

Medical College of Wisconsin and Children’s Hospital of Wisconsin to investigate autoantibody production in autoimmune disorders

Oct. 8, 2012

The Medical College of Wisconsin and Children’s Hospital of Wisconsin Research Institute received a one-year award for more than $375,000 from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases. The award will fund an investigation of the factors involved in regulating the production of autoantibodies, which are antibodies that target an individual’s own tissues. These autoantibodies are linked to autoimmune disorders like lupus and rheumatoid arthritis.

Stephen Gauld, Ph.D., assistant professor of pediatrics in allergy and immunology, and microbiology and molecular genetics, and a researcher at the Research Institute, is the principal investigator for the grant.

The National Institutes of Health estimated in 2005 that between 15 and 24 million Americans suffer from one of the more than 80 diseases in the autoimmune disorder family. Many of these chronic diseases have no cure and disproportionally impact women. Patients are often debilitated by their symptoms and the high costs of a lifetime of treatment.

This project seeks to understand the factors that influence the production of autoantibodies that attack a patient’s own tissues in cases of autoimmune disease. Prior research in Dr. Gauld’s lab has shown that a cell in the immune system, the regulatory T cell, suppresses the production of autoantibodies by other immune cells called B cells. Dr. Gauld will study this reaction to understand how it works and how it can be manipulated to reduce tissue damage and promote patient health.

The results of this study will advance understanding of autoantibody production and help researchers discover novel treatments to slow down or prevent the generation of antibodies that attack the body’s tissues.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Wauwatosa superintendent attends President Barack Obama's 'ConnectED to the Future' event 11/18

» Children's Hospital of Wisconsin moves babies to newly designed NICU 11/18

» City Market closes North Avenue location 11/17

» Early momentum doesn't stay with Tosa East 11/14

» Wauwatosa woman investigated for stealing credit card information from Froedtert Hospital patients 11/13

» Man pointed handgun at front door of Applebee's 11/10

» UW Credit Union branch could break ground in Wauwatosa this month 11/10

» Suburban roundup: Week three of the WIAA football postseason 11/10

» Indulgence Chocolatiers to open in Wauwatosa, and sell Purple Door Ice Cream 11/10

» Former Central States Mortgage CEO to plead guilty to obstruction of justice Updated:  11/6

» Tosa East stuns Brookfield East in volleyball sectional 11/6

» Election roundup: How the Milwaukee suburbs and Lake Country voted Updated:  11/5

» Walker wins Wauwatosa by slimmer margin than the state 11/5

» Walker's neighbors divided over election 11/4

» Authorities identify Wauwatosa man killed by train Updated:  11/4

» Wauwatosa apartments sell for $2.5 million 11/4

» Suburban roundup: Week two of the WIAA football postseason Updated:  11/3

» Power restored to Eisenhower after classes canceled 10/31

» Photo Gallery: WIAA state soccer tourney day one 10/30

» Four-story apartment building proposed for Hall Automotive site 10/30

» Apartments planned at Hall Automotive site in Tosa Updated:  10/30

» Little Read Book in Wauwatosa has author signing Sunday 10/30

» Pedestrian struck, killed by train in Wauwatosa Updated:  10/29

» Suburban roundup: Week one of the WIAA football postseason 10/27

» New Mayfair parking structure to open tonight 10/24

View All Posts Got a tip? Welcome rss

Advertisement

Deal Watch - Milwaukee

Milwaukee's Best Discounts & Deals

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

Local Business Directory

CONNECT