NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
64°
H 64° L 57°
Clear | 7MPH

Medical College of Wisconsin and Children’s Hospital of Wisconsin to investigate autoantibody production in autoimmune disorders

Oct. 8, 2012

The Medical College of Wisconsin and Children’s Hospital of Wisconsin Research Institute received a one-year award for more than $375,000 from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases. The award will fund an investigation of the factors involved in regulating the production of autoantibodies, which are antibodies that target an individual’s own tissues. These autoantibodies are linked to autoimmune disorders like lupus and rheumatoid arthritis.

Stephen Gauld, Ph.D., assistant professor of pediatrics in allergy and immunology, and microbiology and molecular genetics, and a researcher at the Research Institute, is the principal investigator for the grant.

The National Institutes of Health estimated in 2005 that between 15 and 24 million Americans suffer from one of the more than 80 diseases in the autoimmune disorder family. Many of these chronic diseases have no cure and disproportionally impact women. Patients are often debilitated by their symptoms and the high costs of a lifetime of treatment.

This project seeks to understand the factors that influence the production of autoantibodies that attack a patient’s own tissues in cases of autoimmune disease. Prior research in Dr. Gauld’s lab has shown that a cell in the immune system, the regulatory T cell, suppresses the production of autoantibodies by other immune cells called B cells. Dr. Gauld will study this reaction to understand how it works and how it can be manipulated to reduce tissue damage and promote patient health.

The results of this study will advance understanding of autoantibody production and help researchers discover novel treatments to slow down or prevent the generation of antibodies that attack the body’s tissues.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Children's theater presents free performance of "The Frog Prince" tomorrow night 7/30

» Hawaiian grocery crowd-funds commercial kitchen 7/28

» Wauwatosa School District creates new mobile app 7/25

» Tosa responds to concerns about radiation from water meters 7/25

» Menomonee River 14-year-old drowning victim identified 7/21

» Boy drowns in the Menomonee River at Hoyt Park Updated:  7/19

» Former priest accused of theft again fails to appear in court 7/14

» Police connect teens to recent Milwaukee, Wauwatosa carjackings 7/12

» Briggs & Stratton closing Georgia site, will add 370 jobs in Wauwatosa Updated:  7/10

» Section of I-94 to close entirely July 18-21 7/10

» Wauwatosa man killed in crash that snarled Highway 41 traffic 7/10

» Hundreds in Tosa without power 7/1

» Wauwatosa detective sentenced for drug theft 6/24

» Milwaukee suburbs Fourth of July 2014 celebrations 6/20

» Social media photos of the June 18 storms around Southeast Wisconsin 6/18

» Sewage backups may occur with Wauwatosa sewer at full capacity 6/18

» Corner Bakery coming to Mayfair Collection in Wauwatosa 6/11

» Gunfire leads to police chase in Milwaukee, Wauwatosa 6/11

» Wauwatosa Catholic authorized to become International Baccalaureate World School 6/4

» Waukesha YMCA plans to purchase Wauwatosa site 6/4

» New Milwaukee Bucks owners visit Cranky Al's in Wauwatosa 5/29

» Picnic Basket sandwich shop opens in Wauwatosa 5/22

» State to spend $13.5 million on transit to settle Zoo Interchange suit 5/19

» Gem, mineral and fossil show coming this weekend 5/16

» Malt Shoppe plans to focus on beer, fill growlers in Wauwatosa 5/6

View All Posts Got a tip? Welcome rss
Deal Watch - Milwaukee

Milwaukee's Best Discounts & Deals

Local Business Directory

CONNECT