NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
46°
H 55° L 32°
Clear | 8MPH

Medical College of Wisconsin researcher to investigate tuberculosis bacterium

Sept. 24, 2012

The Medical College of Wisconsin (MCW) received a two-year award for more than $400,000 from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to study how the bacterium which causes tuberculosis (TB) survives inside the human body in a latent state which is less susceptible to antibiotics.

Thomas Zahrt, Ph.D., associate professor of microbiology and molecular genetics, is the principal investigator for the grant.

TB is a respiratory disease caused by the bacterium Mycobacterium tuberculosis. More than 8.5 million people worldwide were diagnosed with the disease in 2010, and more than one million died from the illness. The World Health Organization estimates that about one-third of the world’s population (two billion people) has a latent form of TB. In these cases, illness and symptoms can appear a significant amount of time after initial exposure to the TB bacterium, usually due to a secondary event that weakens the immune system.

Dr. Zahrt’s lab is interested in discovering the mechanisms by which M. tuberculosis persists during the latent infection stage, as well as how the bacterium reactivates after months or years of dormancy. This project will study an enzyme believed to be necessary for the bacterium to produce energy and survive during latency.

The findings from this research will generate new insight into the dormant phase of the bacterium responsible for TB, and may reveal new targets for therapies that can treat TB during latency despite its decreased susceptibility to antibiotics.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Ask NOW: When will the lanes on Burleigh Street near Highway 45 be less confusing? 4/15

» In helping others, Bachman became 'Mr. Wauwatosa' 4/12

» City says goodbye to 'Mr. Wauwatosa' 4/9

» Three new Bartolotta restaurants announced for Mayfair Collection 4/8

» Vukmir releases records related to ALEC work 4/4

» Voters disagree with Citizens United ruling 4/2

» Brian Bawden elected to Wauwatosa School Board 4/1

» Jason Kofroth elected District 7 alderman 4/1

» Michael Walsh elected District 4 alderman 4/1

» Matt Stippich wins District 1 aldermanic seat 4/1

» Body found in Tosa identified as James Kieckbusch, 57 4/1

» Body found at border of Elm Grove and Wauwatosa Updated:  4/1

» Michael Lovell's move is a net gain for Milwaukee, business leaders say 3/26

» Wauwatosa police seek suspect in BMO Harris Bank robbery 3/14

» Firm in line for $7.2 million MMSD contract didn't show qualifications Updated:  3/11

» West advances with 75-4 win over James Madison 3/4

» Milwaukeeans share paczki on social media 3/4

» Whitefish Bay finds its tempo, downs Tosa East 2/28

» Messmer rallies to beat Tosa West 2/28

» East's Wheeler's free throws lead to upset of Shorewood 2/25

» Wauwatosa West 'We the People' team making another run in national competition 2/25

» Menomonee River Parkway segment closed to through traffic 2/24

» Salmon's 31 sparks Raiders past Spartans, 50-34 2/21

» Jury fails to reach verdict in firearm silencer case for gun collector 2/20

» Lawyer testifies why he bought silencer during reverse sting Updated:  2/20

View All Posts Got a tip? Welcome rss
Deal Watch - Milwaukee

Milwaukee's Best Discounts & Deals

Local Business Directory

CONNECT