NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
25°
H 28° L 25°
Cloudy | 16MPH

Biomarkers in Heart Failure with Preserved Ejection Fraction

Sept. 13, 2012

Scientists from the Medical College of Wisconsin (MCW) and Froedtert Hospital received a one-year, $50,000 grant from the Clinical and Translational Science Institute of Southeast Wisconsin (CTSI) to study a specific type of heart failure and to identify biomarkers that might allow clinicians to diagnose and treat earlier.

The project, “Biomarkers in Diastolic Dysfunction/Heart Failure with Preserved Ejection Fraction,” is led by primary investigator Jennifer Strande, M.D., Ph.D., assistant professor of cardiovascular medicine at MCW, and cardiologist at Froedtert Hospital. The co-primary investigator is Shama Mirza, Ph.D., assistant professor of biochemistry at MCW.

Half of patients with heart failure have a preserved left ventricular ejection fraction. Having a normal or preserved ejection faction means the heart contracts normally. Heart failure develops in these patients because the ventricles are stiffer and do not relax normally which means less blood enters the heart. If less blood is entering the heart, then less blood is pushed out of the heart. There is no effective treatment for this specific diagnosis. The focus of this work will be to identify biomarkers that contribute to cardiac dysfunction in these patients, which potentially would allow clinicians to diagnose and intervene before irreversible cardiac damage occurs.

This is one of 19 pilot projects being funded in 2012 through CTSI. The goal is to create synergy through collaboration, and studies are specifically designed to lead to major future research support. The projects explore findings that have the potential to be translated into clinical practice and community health, and are led by investigators at the CTSI’s eight partnering institutions: the Medical College of Wisconsin, Marquette University, Milwaukee School of Engineering, UW-Milwaukee, Froedtert Hospital, Children’s Hospital of Wisconsin, the VA Medical Center, and the BloodCenter of Wisconsin.

CTSI is part of a national consortium of top medical research institutions. Working together, the CTSI institutions are committed to improve human health by streamlining science, transforming training environments and improving the conduct, quality and dissemination of clinical and translational research. The CTSI program is led by the National Center for Advancing Translational Sciences, part of the National Institutes of Health.

Support for the Pilot Award Program comes from the National Institutes of Health, the John and Jeanne Byrnes CTSI Award, and both MCW’s Advancing a Healthier Wisconsin program, and MCW’s Biotechnology and Bioengineering Center.
 

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Woman drives drunk to pick up drunken driver from police station 12/10

» Suspects of five related burglaries in Wauwatosa arrested, charged 12/9

» Woman threatens to stab Sak's employee after retail theft 12/9

» Wauwatosa aderman runs for Milwaukee County supervisor 12/8

» Anonymous email threatens Wauwatosa East High School 12/5

» 600 bowlers, volleyball players to compete at the Special Olympics Wisconsin on Saturday 12/4

» Kindergarten registration sessions announced 12/3

» Oconomowoc man, Eisenhower teacher, dies unexpectedly 11/29

» HomeGoods coming to Mayfair Collection 11/24

» Wauwatosa superintendent attends President Barack Obama's 'ConnectED to the Future' event 11/18

» Children's Hospital of Wisconsin moves babies to newly designed NICU 11/18

» City Market closes North Avenue location 11/17

» Early momentum doesn't stay with Tosa East 11/14

» Wauwatosa woman investigated for stealing credit card information from Froedtert Hospital patients 11/13

» Man pointed handgun at front door of Applebee's 11/10

» UW Credit Union branch could break ground in Wauwatosa this month 11/10

» Suburban roundup: Week three of the WIAA football postseason 11/10

» Indulgence Chocolatiers to open in Wauwatosa, and sell Purple Door Ice Cream 11/10

» Former Central States Mortgage CEO to plead guilty to obstruction of justice Updated:  11/6

» Tosa East stuns Brookfield East in volleyball sectional 11/6

» Election roundup: How the Milwaukee suburbs and Lake Country voted Updated:  11/5

» Walker wins Wauwatosa by slimmer margin than the state 11/5

» Walker's neighbors divided over election 11/4

» Authorities identify Wauwatosa man killed by train Updated:  11/4

» Wauwatosa apartments sell for $2.5 million 11/4

View All Posts Got a tip? Welcome rss

Advertisement

Deal Watch - Milwaukee

Milwaukee's Best Discounts & Deals

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

Local Business Directory

CONNECT