NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
28°
H 34° L 19°
Light Snow | 7MPH

Medical College of Wisconsin Researcher to Study Lou Gehrig’s Disease

Sept. 8, 2012

Medical College of Wisconsin Researcher to Study Lou Gehrig’s Disease

The Medical College of Wisconsin has received a $40,000 grant from the ALS Association’s Jeff Kaufman Fund to study the impact of skeletal muscle on the progression of ALS, or Lou Gehrig’s Disease, as it’s commonly known.

Allison Ebert, Ph.D., assistant professor of cell biology, neurobiology and anatomy, is the primary investigator of the grant.

ALS is an incurable and fatal disease in which muscle progressively weakens, resulting in paralysis.  The nerve cells which control the body’s movements deteriorate and die; the neurons in the brain and spine follow.  In the United States, 14 cases of ALS are diagnosed each day. The average expected survival time is three to five years, and at any given time, approximately 30,000 people in the U.S. are living with ALS.

In her research project, Dr. Ebert plans to develop a novel system to generate and characterize the skeletal muscle from ALS patient’s induced pluripotent stem cells (iPSCs), which are stem cells generated from adult tissue.  Studies suggest that the loss of neurons and skeletal muscle connection may occur very early in patients with ALS, which presents a potential therapeutic target.  Dr. Ebert will use iPSCs from patients with ALS and health adults to create skeletal muscle.  That muscle tissue will be combined in the lab with iPSC derived neurons to observe the interactions between the two in ALS patients versus the healthy controls.

“Understanding the progression of this disease at a molecular level will help us target areas for early detection,” said Dr. Ebert.  “I am grateful to the ALS Association for its generous support of our research.”

The ALS Association’s Jeff Kaufman Fund, established to fund cutting-edge research from proceeds of the ALS Association-Wisconsin Chapter’s Evening of Hope.”

“We are very pleased to announce these new research grants to some of the most promising ALS researchers in the U.S. and around the world,” said Lucie Bruijn, Ph.D., Chief Scientist for The ALS Association. “The ALS Association looks forward to sharing the results of these diverse studies, which we hope will provide pieces to the complex puzzle of this devastating disease.”

The studies will help understand the disease process of ALS, and could lead to potential targeted therapies in the future.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Wauwatosa Senior Commission surveying seniors 1/29

» Answers and winners of the Suburban Selfies contest revealed! 1/29

» Four similar thefts reported at Wisconsin Lutheran College 1/29

» Meijer to open Wauwatosa store in August 1/28

» Wauwatosa committee recommends e-cigarette restrictions 1/28

» Two businesses in same building burglarized 1/27

» Wrong-way driver identified as person killed in I-94 crash 1/24

» Wauwatosa offers 'Citizen's Academy' course 1/21

» Packers playoff run prompts fond memories 1/18

» Suburban Selfies contest extended through Jan. 25; two selfie solutions to get you started! 1/15

» Wauwatosa school district adds computer science course 1/14

» Wauwatosa man dead after crash on Miller Park Way 1/12

» Wauwatosa stamp factory to become shopping center 1/12

» Mayfair Collection developer buys nearby site for retail project Updated:  1/8

» Plaque honors memory of Wauwatosa Police Officer Jennifer Sebena 1/8

» Three candidates vie to represent Wauwatosa on Milwaukee County Board 1/7

» Developers reveal plans for housing at Wauwatosa's Mayfair Collection 1/6

» Milwaukee man dead after crash in Wauwatosa 1/6

» Coast Guard member gets 5 months confinement for assault 1/6

» Friday deadline for Wauwatosa Distinguished Citizen nominations 1/5

» Wauwatosans organize rally in support of local police 1/2

» Brown's tip in makes Wauwatosa West upset winner 12/31

» Wauwatosa East to establish Athletic Hall of Fame in 2015 12/30

» Wauwatosa's All-City Read invites students, residents for essay contest 12/30

» Nordstrom to open Oct. 23, 2015 at Mayfair 12/30

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.


Local Business Directory

CONNECT