Medical College of Wisconsin researchers seek to improve tests for predicting heart disease
The Medical College of Wisconsin (MCW) received a four-year, $2.5 million award from the National Institutes of Health’s National Heart, Lung and Blood Institute to develop a more precise clinical test for predicting a patient’s risk of developing heart disease.
Kirkwood A. Pritchard, Ph.D., professor of surgery, pharmacology and toxicology and director of translational vascular biology program at MCW and a member of the Children’s Hospital Research Institute, is the principal investigator for the grant. Dr. Pritchard’s co-principal investigator is Mary G. Sorci-Thomas, Ph.D., professor of pathology and lipid sciences at Wake Forest University School of Medicine in Winston-Salem, N.C.
Heart disease is the leading cause of death in Wisconsin, resulting in more than 16,000 deaths annually-- approximately one-third of all deaths in the state. The prevalence of this disease may increase as rates of obesity and hypertension are predicted to rise in Wisconsin.
This research seeks to aid physicians in predicting and preventing heart disease. Recent studies have shown the importance of measuring the function of high-density lipoprotein (HDL) cholesterol, known as “good” cholesterol. Measuring HDL function is more accurate than traditional tests, which measure HDL levels, at predicting which patients will develop heart disease. Current tests for the function of HDL cholesterol are complex and too cumbersome to be useful in a clinical setting.
Dr. Pritchard and Dr. Sorci-Thomas will work to develop novel tests for HDL functionality that are simpler and less time-consuming for practitioners in a clinical setting. Their work may lead to a better diagnostic tool for predicting a person’s risk of heart disease, which would meet a great need in helping prevent and effectively treat heart disease.
Your link to the biggest stories in the suburbs delivered Thursday mornings.
Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter Get the Newsletter!
- Adolescent patients needed for study on pain
- Care and quality of life for older, rural HIV-positive adults
- HGTV’s House Hunters Returns to Southeastern Wisconsin to Feature Flat Rate Home Services’ Employee
- International Expert Dr. Michele Borba to Speak at Alverno College Character Education Conference
- Stars and Stripes Honor Flight-The Final Thank You
- Meijer Announces Opening Dates for First Wisconsin Supercenters
- Comprehensive Eye Exams Can Help Re-engage Patients Into Care for Certain Chronic Conditions, With the Potential to Help Improve Health and Reduce Costs
- Tosa East Junior Achieves Eagle Scout Award
- G.A.P.C. Hosts Annual Strawberry Fest June 14th
- Milwaukee to Host 2015 USA Ultimate Division 1 College Championships, May 22-25 at Uihlein Park