Medical College of Wisconsin Receives Grant from the St. Baldricks Foundation for Cancer Research

Aug. 17, 2012

The Medical College of Wisconsin (MCW) received a one year, $50,275 supportive care research grant from the St. Baldrick’s Foundation to study new therapies for hearing loss in pediatric cancer patients.

Fritz Sieber, Ph.D., professor of pediatrics and medicine at MCW with joint appointments in the Department of Cell Biology, Neurobiology & Anatomy and the Department of Microbiology and Molecular Genetics, and a researcher at Children’s Hospital of Wisconsin Research Institute, is the primary investigator of the grant. Co-investigators are Christina Runge, Ph.D., associate professor of otolaryngology and communication sciences at MCW; and David Friedland, M.D., Ph.D., professor and vice chair of otolaryngology and communication sciences at MCW.

About half of children and adolescents who become long-term cancer survivors develop therapy-induced hearing loss that is cumulative and irreversible. The patients most at risk are those with brain tumors and other cancers that require treatment with drugs called “platins,” combined with radiation to the head and neck.

This hearing loss adversely affects speech, reading ability, communication, academic performance and overall psychosocial development, which sometimes leads to low self-esteem and social isolation.

In this research project, Dr. Sieber and his team will investigate the use of high doses of dietary selenium to prevent cisplatin-induced hearing loss. The researchers will use a rat model to activate pathways to prevent hearing loss more effectively than conventional antioxidants.

“Selenium has been shown to be effective in mitigating other forms of radiation injury to normal tissue,” said Dr. Sieber. “We are hopeful that selenium will be shown to reduce this devastating side effect of cancer treatments, and we are grateful for the St. Baldrick’s Foundation for their support of this project.”

Dan Devine, the mayor of West Allis, Wis., which held its third St. Baldrick’s event this summer, said, “These events always bring the community together, are lots of fun and raise money for an incredibly valuable cause. Learning that the money raised by the St. Baldrick’s Foundation will go directly to the Medical College of Wisconsin, it makes it even more special.”
 

Community Watch

» Irish Fest gears up for week of classes at Tosa's CelticMKE Center 6/28

» Tosa Skateboarders United hosts first event since opening of new park 6/28

» Friends of Center Street Park will launch new barbecue event July 3 6/28

» Long-tenured sports writer Sky Skibosh heads into retirement, sort of 6/26

» Family, friends of man killed by Wauwatosa officer want answers 6/25

» Tosa man with gun trove to plead guilty of illegal dealing 6/24

» Wauwatosa endorses bus rapid transit route, more approvals needed Updated:  6/23

» Video: Tosa Top 5: Five things you need to know about in Wauwatosa this week 6/23

» Wauwatosa officer fatally shoots man at Madison Park 6/23

» Wauwatosa Public Library announces list of summer events 6/22

» Blood drives scheduled for Milwaukee County during month of July 6/22

» Two lanes on Wauwatosa's Harmonee Bridge to close Thursday 6/22

» Milwaukee Co. Zoo welcomes baby harbor seal, bonobo 6/22

» Teens accused of trying to rob Tosa resident with BB gun Updated:  6/22

» Hidden Tosa: Inside the Wauwatosa Police Department 6/22

» Offense holding back Wauwatosa West baseball team 6/21

» Wauwatosa East baseball wins four conference games 6/21

» Former Wauwatosa West star Austin Jones drafted by Chicago Cubs in 26th round 6/21

» East Tosa Gran Prix returns to Wauwatosa June 26 6/21

» Wauwatosa School Board votes to give teachers a bump in pay Updated:  6/20

» New records for Tosa Swim Club 6/20

» Tosa customers temporarily lose power after squirrel causes blown fuse 6/20

» Video: VISIT Milwaukee, city of Wauwatosa launch new tourism video 6/20

» Mayfair mall's Sephora draws police attention since February Updated:  6/17

» Pool at Hoyt Park running again following mid-week mechanical failure 6/17

View All Posts Got a tip? Welcome rss

Best Summer Ever

 

We've made it easy for you to get out and go this summer. From hitting the trails for a bike ride or walk, to where to find beer gardens in the area, to the best places to swim in Waukesha County to the best summer drinks and summer reads, check out our 2016 summer guide.

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where our Wauwatosa reporter explores the closed down and closed off parts of Wauwatosa.

Advertisement

CONNECT