Our privacy policy has changed. By using this site, you agree to the Privacy Policy and Terms of Use. Dismiss

Medical College of Wisconsin Receives Grant from the St. Baldricks Foundation for Cancer Research

Aug. 17, 2012

The Medical College of Wisconsin (MCW) received a one year, $50,275 supportive care research grant from the St. Baldrick’s Foundation to study new therapies for hearing loss in pediatric cancer patients.

Fritz Sieber, Ph.D., professor of pediatrics and medicine at MCW with joint appointments in the Department of Cell Biology, Neurobiology & Anatomy and the Department of Microbiology and Molecular Genetics, and a researcher at Children’s Hospital of Wisconsin Research Institute, is the primary investigator of the grant. Co-investigators are Christina Runge, Ph.D., associate professor of otolaryngology and communication sciences at MCW; and David Friedland, M.D., Ph.D., professor and vice chair of otolaryngology and communication sciences at MCW.

About half of children and adolescents who become long-term cancer survivors develop therapy-induced hearing loss that is cumulative and irreversible. The patients most at risk are those with brain tumors and other cancers that require treatment with drugs called “platins,” combined with radiation to the head and neck.

This hearing loss adversely affects speech, reading ability, communication, academic performance and overall psychosocial development, which sometimes leads to low self-esteem and social isolation.

In this research project, Dr. Sieber and his team will investigate the use of high doses of dietary selenium to prevent cisplatin-induced hearing loss. The researchers will use a rat model to activate pathways to prevent hearing loss more effectively than conventional antioxidants.

“Selenium has been shown to be effective in mitigating other forms of radiation injury to normal tissue,” said Dr. Sieber. “We are hopeful that selenium will be shown to reduce this devastating side effect of cancer treatments, and we are grateful for the St. Baldrick’s Foundation for their support of this project.”

Dan Devine, the mayor of West Allis, Wis., which held its third St. Baldrick’s event this summer, said, “These events always bring the community together, are lots of fun and raise money for an incredibly valuable cause. Learning that the money raised by the St. Baldrick’s Foundation will go directly to the Medical College of Wisconsin, it makes it even more special.”
 

Community Watch

» Video: Reporter takes us along the 2016 Run Tosa Run 5/23

» Tosa Top 5: Five things you need to know about in Wauwatosa this week 5/20

» Suspects charged in string of armed robberies through Wauwatosa, Milwaukee Updated:  5/19

» New Mayfair GM announces plans for a Z Gallerie furniture store Updated:  5/18

» Wauwatosa East baseball team will rely on defense, depth in 2016 5/18

» Wauwatosa East softball teams beats West Allis Central in twinbill 5/18

» Campus News: May 19 5/18

» Sports Shorts: May 19, 2016 5/18

» Wauwatosa East girls soccer team crushes West Allis Central, 11-0 5/18

» Wauwatosa West girls soccer team seeks Woodland title 5/18

» Wauwatosa East's Ryan Kelnhofer to play in summer All-Star game 5/18

» Wauwatosa's Folley takes first in Greco-Roman Tourney 5/18

» Call for votes to name new giraffe at Milwaukee County Zoo 5/18

» Wauwatosa golfers finish fourth in fifth GMC mini-meet 5/18

» Wauwatosa Swordfish set 10 records at swimming meet 5/18

» Sports Notes: May 19, 2016 5/18

» Initial Reaction Podcast: A chat with award-winning sportscaster Dennis Krause Updated:  5/17

» Tosa firefighters serve up meals for families in need 5/16

» Barre District looks to open second studio near Wauwatosa 5/16

» Maggiano's Little Italy in Tosa celebrates patio grand opening Updated:  5/16

» Meijer launches campaign to benefit Tosa Community Food Pantry 5/13

» Video: Tosa Top 5: Five things you need to know about in Wauwatosa this week Updated:  5/13

» Wauwatosa apartment fire causes $40,000 in damage, no injuries reported Updated:  5/13

» 'Bow Tie,' deer illegally hunted in Wauwatosa, finally returns home Updated:  5/13

» Wauwatosa West grad survives London car crash, thrives in collegiate tennis Updated:  5/12

View All Posts Got a tip? Welcome rss

Best Summer Ever

 

We've made it easy for you to get out and go this summer. From hitting the trails for a bike ride or walk, to where to find beer gardens in the area, to the best places to swim in Waukesha County to the best summer drinks and summer reads, check out our 2016 summer guide.

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where our Wauwatosa reporter explores the closed down and closed off parts of Wauwatosa.

Advertisement

CONNECT