Our privacy policy has changed. By using this site, you agree to the Privacy Policy and Terms of Use. Dismiss

Collaborative Research Team to Study Immune Therapy for Multiple Myeloma

July 7, 2012

A collaborative research team received a one-year, $20,000 grant from the Clinical and Translational Science Institute of Southeast Wisconsin (CTSI) to study a novel immunotherapy approach for the treatment of multiple myeloma.

Jill Gershan, Ph.D., assistant professor of pediatrics (hematology/oncology) at the Medical College of Wisconsin (MCW) and an investigator at Children’s Research Institute, the research arm of Children’s Hospital of Wisconsin, is the primary investigator of the grant. Co-primary investigators from Froedtert & The Medical College are William Drobyski, M.D.; Carolyn Taylor, Ph.D.; and Michael Bishop, M.D. Meghen Browning, M.D., and Byron Johnson, Ph.D., conduct research at MCW and at Children’s Research Institute.

Multiple myeloma is a blood cancer with an average survival prognosis of only 3-5 years as most patients succumb to their disease despite aggressive chemotherapy and hematopoietic stem cell transplantation (HSCT). Therefore, it is critical that novel treatments for cancers such as multiple myeloma are developed to prevent relapse and improve overall survival. Adjuvant immunotherapy administered early post-transplant offers a promising approach to reduce multiple myeloma relapse. The goal of immune therapy is to destroy tumor through the activation of tumor-specific cytolytic lymphocytes and induce a memory response whereby immune cells will continue surveillance and destruction of tumor cells long-term. The aim of this pre-clinical study is to determine the optimal combination of immune therapies that elicit the best anti-tumor effect in a murine model of multiple myeloma.

This is one of 19 pilot projects being funded in 2012 through CTSI. The goal is to create synergy through collaboration, and studies are specifically designed to lead to major future research support. The projects explore findings that have the potential to be translated into clinical practice and community health, and are led by investigators at the CTSI’s eight partnering institutions: the Medical College of Wisconsin, Marquette University, Milwaukee School of Engineering, UW-Milwaukee, Froedtert Hospital, Children’s Hospital of Wisconsin, the VA Medical Center, and the BloodCenter of Wisconsin.

CTSI is part of a national consortium of top medical research institutions. Working together, the CTSI institutions are committed to improve human health by streamlining science, transforming training environments and improving the conduct, quality and dissemination of clinical and translational research. The CTSI program is led by the National Center for Advancing Translational Sciences, part of the National Institutes of Health.

Support for the Pilot Award Program comes from Advancing a Healthier Wisconsin (AHW), the National Institutes of Health (NIH), the Biotechnology and Bioengineering Center (BBC) and the John and Jeanne Byrnes CTSI Award.

Community Watch

» Shoulder mount of beloved deer 'Bow Tie' to return to Milwaukee Co. Parks 5/5

» Video Tosa Top 5: Five things you need to know about in Wauwatosa this week 5/5

» Sports Shorts: May 5, 2016 5/4

» Wauwatosa East batters come to life against Brown Deer, Brookfield East 5/4

» Wauwatosa East boys track team finishes fourth at Dan Benson Invite 5/4

» Wauwatosa golfers win Panther Invite 5/4

» Wauwatosa West softball team holds on to nip Port Washington 5/4

» Wauwatosa East girls track team finishes fourth at Dan Benson Invite 5/4

» Adams leads the way for Wauwatosa West girls at Dan Benson Invite 5/4

» Wauwatosa West boys track and field team finishes fifth at Dan Benson Invite 5/4

» Initial Reaction Podcast: Schobert, Watt, Packers and social media foibles of NFL Draft 5/2

» Travis Hudson earns third straight volleyball National Player of the Year Award 5/2

» Wauwatosa East student named 2016 presidential scholar 5/2

» Tosa Tonight announces 2016 concert headliners 5/2

» 360NOW: Wander Wawatosa's village 4/29

» Milwaukee Co. Zoo welcomes new female giraffe calf 4/29

» Video Tosa Top 5: Five things you need to know about in Wauwatosa 4/28

» Wauwatosa seeks volunteers for focus groups on city communication 4/28

» Show about solitary confinement encourages discussion, activism 4/28

» Annual Tosa Night Out celebration will relocate to Milwaukee County Zoo Updated:  4/27

» District leaders question use of Wauwatosa schools as voting locations Updated:  4/27

» Area businesses collaborate to create the 'Cranky Sammie' in East Tosa 4/27

» Wauwatosa Sports Notes: Players sign with colleges, baseball fundraiser, more 4/26

» Wauwatosa West sprinters stand out at Kansas Relays 4/26

» Wauwatosa West' Hannah-Howell, Jefferson shine at Sun Prairie Track Meet 4/26

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where our Wauwatosa reporter explores the closed down and closed off parts of Wauwatosa.

Advertisement

CONNECT