NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
27°
H 28° L 27°
Light Snow | 12MPH

Medical College researcher to study potential treatment for botulism

July 2, 2012

The Medical College of Wisconsin (MCW) received a two-year, $420,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to investigate a promising biological avenue for treating nerves affected by botulism.

Joseph T. Barbieri, Ph.D., professor of microbiology and molecular genetics and director of the Medical Scientist Training Program at MCW, is the principal investigator for the grant who will collaborate with MCW colleagues Allison Ebert, Ph.D., assistant professor of cell biology, neurobiology and anatomy, and Jung-Ja Kim, Ph.D., professor of biochemistry, to conduct this research.

Clostridium botulinum bacteria produce a nerve toxin that can cause botulism, a rare paralytic disease that afflicts approximately 145 people each year in the United States. Botulinum toxin is the most toxic protein for humans and classified as a “Category A Select Agent.” There is a limited supply of the vaccine used to treat the illness and no other approved therapies exist.

Dr. Barbieri will study a method to deliver therapies to diseased nerves. The effectiveness of this method for treating specific nerves affected by the botulinum toxin will be tested in mouse models.

This is one of the first R21/R33 grants, a new funding mechanism at the NIH, awarded to MCW. A two-year R21 grant may be transitioned into a longer-term, higher budget R33 grant if milestones are met.

This research aims to develop targeted, effective treatments for botulism, which may be useful in generating therapies for other diseases of the nervous system.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Twirly Birds vintage store plans return to Wauwatosa 3/2

» Dry cleaner seeks expansion into old City Market in Wauwatosa 3/2

» Construction worker dies in machinery accident at Zoo Interchange project 2/28

» 'Momastery' author coming to Wauwatosa 2/27

» Wauwatosa's Folley and Reagan advance to state wrestling semis 2/26

» Wauwatosa East teacher Barb Bruesewitz named ProStart Teacher of the Year 2/26

» Pancake breakfast Sunday will raise money for scholarships 2/25

» Read the winning essays in Tosa's All-City Read contest 2/24

» Victim in fatal Wauwatosa house fire was 3-year-old girl Updated:  2/23

» MMSD commission OKs $6.4 million flood control project 2/23

» Medical examiner identifies 3-year-old who died in Wauwatosa house fire 2/22

» Menomonee flood plan would free part of stream from culvert 2/20

» Five idling cars stolen in one week in Wauwatosa 2/20

» Two men attempted to defraud two Apple stores with fake iPhones 2/20

» National German Exam qualifies some students for study abroad 2/20

» Personal finance students at Wauwatosa West guess value of items in "The Twelve Days of Christmas" 2/19

» Wauwatosa woman charged for armed robbery in Brookfield 2/19

» Men arrested for fighting at The Cheesecake Factory 2/19

» Tosa Skatepark brick sale ending Feb. 28 2/19

» Residents face off over proposed parking structure at Wisconsin Lutheran College 2/17

» Wauwatosa Alderman Wilke ousted from county supervisor race in primary 2/17

» Wauwatosa East High School students won Scholastic Art Awards 2/17

» Two Wauwatosa students won Scholastic Writing Awards 2/17

» Explore 'The Space Race' at the Wauwatosa planetarium's upcoming program 2/17

» Protesters march on Scott Walker's Wauwatosa home to decry state budget cuts Updated:  2/16

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporter Rory Linnane explores the closed down and closed off parts of Wauwatosa.

2015 Writing Contest

 

(Click image for details)


Local Business Directory

CONNECT