NOW:53208:USA01012
http://widgets.journalinteractive.com/cache/JIResponseCacher.ashx?duration=5&url=http%3A%2F%2Fdata.wp.myweather.net%2FeWxII%2F%3Fdata%3D*USA01012
66°
H 66° L 59°
Clear | 0MPH

Medical College researcher to study potential treatment for botulism

July 2, 2012

The Medical College of Wisconsin (MCW) received a two-year, $420,000 grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to investigate a promising biological avenue for treating nerves affected by botulism.

Joseph T. Barbieri, Ph.D., professor of microbiology and molecular genetics and director of the Medical Scientist Training Program at MCW, is the principal investigator for the grant who will collaborate with MCW colleagues Allison Ebert, Ph.D., assistant professor of cell biology, neurobiology and anatomy, and Jung-Ja Kim, Ph.D., professor of biochemistry, to conduct this research.

Clostridium botulinum bacteria produce a nerve toxin that can cause botulism, a rare paralytic disease that afflicts approximately 145 people each year in the United States. Botulinum toxin is the most toxic protein for humans and classified as a “Category A Select Agent.” There is a limited supply of the vaccine used to treat the illness and no other approved therapies exist.

Dr. Barbieri will study a method to deliver therapies to diseased nerves. The effectiveness of this method for treating specific nerves affected by the botulinum toxin will be tested in mouse models.

This is one of the first R21/R33 grants, a new funding mechanism at the NIH, awarded to MCW. A two-year R21 grant may be transitioned into a longer-term, higher budget R33 grant if milestones are met.

This research aims to develop targeted, effective treatments for botulism, which may be useful in generating therapies for other diseases of the nervous system.

This site uses Facebook comments to make it easier for you to contribute. If you see a comment you would like to flag for spam or abuse, click the "x" in the upper right of it. By posting, you agree to our Terms of Use.

Suburban News Roundup

E-mail Newsletter

Your link to the biggest stories in the suburbs delivered Thursday mornings.


Enter your e-mail address above and click "Sign Up Now!" to begin receiving your e-mail newsletter
Get the Newsletter!

Login or Register to manage all your newsletter preferences.

Community Watch

» Second design workshop for Tosa skate park is Thursday 8/26

» Milwaukee gets its first green bike lane installed in Riverwest 8/26

» Former Wauwatosa priest pleads not guilty to embezzlement charges 8/26

» The social media story of Wauwatosa West at Wauwatosa East football 8/23

» Trojans rule the city another year 8/22

» Preps football photos of the week: Aug. 22 8/22

» Poll: Who will win the Battle of Wauwatosa: West or East? 8/21

» Wauwatosa students hit same average ACT score as last year 8/20

» Twirly Birds vintage and hand-craft store moves to Waukesha 8/19

» Paving complete on North Avenue 8/18

» Nicolet cancels varsity football season 8/14

» East Tosa business owners clash over BID 8/11

» Weed found at Macy's inside Mayfair mall 8/11

» Woman leaves dog in hot car, charged with animal cruelty 8/1

» Children's theater presents free performance of "The Frog Prince" tomorrow night 7/30

» Hawaiian grocery crowd-funds commercial kitchen 7/28

» Wauwatosa School District creates new mobile app 7/25

» Tosa responds to concerns about radiation from water meters 7/25

» Menomonee River 14-year-old drowning victim identified 7/21

» Boy drowns in the Menomonee River at Hoyt Park Updated:  7/19

» Former priest accused of theft again fails to appear in court 7/14

» Police connect teens to recent Milwaukee, Wauwatosa carjackings 7/12

» Briggs & Stratton closing Georgia site, will add 370 jobs in Wauwatosa Updated:  7/10

» Section of I-94 to close entirely July 18-21 7/10

» Wauwatosa man killed in crash that snarled Highway 41 traffic 7/10

View All Posts Got a tip? Welcome rss
Deal Watch - Milwaukee

Milwaukee's Best Discounts & Deals

Local Business Directory

CONNECT