Our privacy policy has changed. By using this site, you agree to the Privacy Policy and Terms of Use. Dismiss

Medical College researcher to study new pathway for psoriasis

June 20, 2012

The Medical College of Wisconsin received a two-year, $200,000 grant from the National Psoriasis Foundation to study the pathogenesis of psoriasis and to identify new drugs that may benefit patients.

Sam Hwang, M.D., Ph.D., and Thomas J. Russell Family/Milwaukee Community Dermatologists Chair and professor of dermatology, is the principal investigator for the grant.

Approximately 7.5 million Americans are living with psoriasis, an autoimmune disease in which dead skin cells accumulate and cause irritation that appears as itchy scales or dry patches. Symptoms can be treated, but there is no cure, and the severity of the disease ranges from mild discomfort to complete disability. Complications include arthritis, ischemic heart disease, and depression. Dr. Hwang’s lab identified two proteins (a chemokine receptor called CCR6 and it binding protein) in prior studies of psoriasis development that appear to have significant involvement in the disease. In this study, Dr. Hwang will investigate these proteins further to better understand how they impact the pathogenesis of psoriasis. Dr. Hwang will also use computer modeling to discover drugs that may block the actions of these proteins and thus, potentially, improve therapy for patients with this disease.

This study may verify a pathway for psoriasis and provide new information about its cause. The project may also identify new treatments for psoriasis and other diseases influenced by the proteins Dr. Hwang is investigating.

This special award is called the Lutto Translational Grant in honor of Seymour and Rebecca Lutto, who made this research possible with a gift to the National Psoriasis Foundation. They sought to memorialize their son Lawrence Lutto by advancing scientific knowledge regarding the cause and treatment of psoriasis. This year, the National Psoriasis Foundation awarded to $2.06 million to 26 scientists, which is the greatest number of grants and dollars ever given by the foundation.

Community Watch

» Video Tosa Top 5: Five things you need to know about in Wauwatosa this week 4/28

» Wauwatosa seeks volunteers for focus groups on city communication 4/28

» Show about solitary confinement encourages discussion, activism 4/28

» Annual Tosa Night Out celebration will relocate to Milwaukee County Zoo Updated:  4/27

» District leaders question use of Wauwatosa schools as voting locations Updated:  4/27

» Area businesses collaborate to create the 'Cranky Sammie' in East Tosa 4/27

» Wauwatosa Sports Notes: Players sign with colleges, baseball fundraiser, more 4/26

» Wauwatosa West sprinters stand out at Kansas Relays 4/26

» Wauwatosa West' Hannah-Howell, Jefferson shine at Sun Prairie Track Meet 4/26

» Wauwatosa West tennis team wins three of four at Raider/Trojan Invite 4/26

» Wauwatosa golfers finish fifth at first GMC mini meet 4/26

» Wauwatosa East kickers go 2-1 at Mt. Prospect Invitational, lose to DSHA, beat Homestead 4/26

» Wauwatosa West soccer team tied for first in Woodland with 4-0 record 4/26

» Principal's racial comment to Wauwatosa West student sparks protest at school Updated:  4/25

» Severe thunderstorm watch in effect 4/25

» Political memorabilia appraiser makes stop in Wauwatosa 4/25

» Initial Reaction Podcast: Previewing NFL Draft with Rob Reischel and Nathan Tanguay 4/25

» Cheryl Berdan steps in as Wauwatosa Common Council president 4/22

» Video Tosa Top 5: Five things you need to know about in Wauwatosa this week 4/21

» Wauwatosa business Nurturing the Nest offers postpartum support to moms, dads Updated:  4/21

» Initial Reaction Podcast: Realignment in area conferences and the status of girls/women's basketball in Wisconsin 4/21

» Walled garden, dog park to replace Wauwatosa's aging Eschweiler buildings 4/20

» Matt Kender is Wauwatosa East's new football coach 4/20

» Sports Shorts: April 21, 2016 4/20

» Milwaukee County Zoo welcomes new female red panda 4/20

View All Posts Got a tip? Welcome rss

Advertisement

Advertisement

Hidden Tosa

 

"Hidden Tosa" is a semi-regular feature where reporters Rory Linnane or Rachel Minske explore the closed down and closed off parts of Wauwatosa.

Advertisement

Local Business Directory

CONNECT